Imatinib Impurity 44 CAS CATO-C4X-106844
| CAS No. | CATO-C4X-106844 |
| Molecular Formula | C53H51N12O2 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Imatinib Impurity 44 (CAS CATO-C4X-106844, C53H51N12O2Cl) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Imatinib Impurity 44 (C53H51N12O2Cl) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Imatinib Impurity 44 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C53H51N12O2 Cl |
| Molecular Weight | 923.52 g/mol |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 34.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 12 |
Related Imatinib Standards
- Imatinib Impurity 10 (CAS 1026753-54-7)
- 6-Methyl Imatinib (CAS 1032314-85-4)
- Imatinib Impurity 17 (CAS 106261-49-8)
- Imatinib Impurity 48 (CAS 106261-64-7)
- Imatinib-d8 (CAS 1092942-82-9)
- Imatinib Impurity 18 (CAS 112696-91-0)
- Imatinib Impurity 48 (CAS 1131605-15-6)
- Imatinib-d3 (N-methyl-d3) (CAS 1134803-18-1)
Recommended Standards
- Upadacitinib Impurity 119 (CAS CATO-C4X-2405119)
- Alectinib Impurity 52 (CAS CATO-C4X-283652)
- Trelagliptin Impurity 28 (CAS CATO-C4X-104628)
- 1-(1H-indol-3-yl)-3,3-dimethylbutan-2-one (CAS 1351393-64-0)
- Azide-C2-SS-C2-biotin (CAS 1620523-64-9)
- 6-ethyl-1-indanone (CAS 42348-88-9)
- 2-((6-Acetamidopyridazin-3-yl)thio)-N-(2-fluorophenyl)acetamide (CAS 1021075-91-1)
- 4-Bromo-3-chlorotoluene (CAS 6627-51-6)
- Sulpiride Impurity 19 (CAS 326882-44-4)
- Neuropeptide Y (free acid) (human, rat) trifluoroacetate salt (CAS 99575-89-0)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com