Erlotinib Impurity 66 CAS CATO-C4X-106966
| CAS No. | CATO-C4X-106966 |
| Molecular Formula | C12H15NO7 |
| Molecular Weight | 285.25 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Erlotinib Impurity 66.
As a process- or degradation-related impurity, Erlotinib Impurity 66 (CAS CATO-C4X-106966, C12H15NO7) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Erlotinib Impurity 66 (C12H15NO7) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 6.0, corresponding to approximately 6 ring(s) or double-bond equivalent(s). With a molecular weight of 285.25 g/mol, it falls into the medium-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Erlotinib Impurity 66 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H15NO7 |
| Molecular Weight | 285.25 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 1 |
Related Erlotinib Standards
- Erlotinib Impurity 65 (CAS CATO-C4X-106965)
- Erlotinib Impurity 38 (CAS 574738-66-2)
- Erlotinib impurity 129 (CAS CATO-C4X-1069129)
- Erlotinib Impurity 52 (CAS 236750-62-2)
- Erlotinib Impurity 28 (CAS CATO-C4X-106928)
- Erlotinib Impurity 29 (CAS CATO-C4X-106929)
- Erlotinib Impurity 20 (CAS 938185-06-9)
- Erlotinib Impurity 17 (CAS 1417161-98-8)
Recommended Standards
- Pranoprofen Impurity 17 (CAS CATO-C4X-181117)
- 4-Nitrophenylα-L-Rhamnopyranoside (CAS 18918-31-5)
- Pranoprofen Impurity 64 (CAS CATO-C4X-181164)
- 4-Nitrophenyl α-L-Fucopyranoside (CAS 10231-84-2)
- Tryptophan impurity 32 (CAS 2306500-74-1)
- Mirogabalin Impurity 217 (CAS CATO-C4X-2924217)
- Eltrombopag Impurity 41 (CAS 17933-03-8)
- Vancomycin-d12 trifluoroacetate Salt (CAS CATO-CCAD303342)
- 3-(5-Bromo-2-methoxyphenyl)-3-hydroxypropanenitrile (CAS 1521554-58-4)
- Cefdinir Impurity 72 (CAS CATO-C4X-121072)
- 2,6-Diaminopyrazine (CAS 41536-80-5)
- Potassium 3-Indoleacetate (CAS 2338-19-4)
- 1-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-4-((5-((2,4-dichlorobenzyl)thio)-4-phenyl-4H-1,2,4-triazol-3-yl)methyl)piperazine (CAS 338979-17-2)
- Tirzepatide Impurity 52 (CAS CATO-C4X-324052)
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