Abiraterone Impurity 45 CAS CATO-C4X-107045
| CAS No. | CATO-C4X-107045 |
| Molecular Formula | C19H27IO2 |
| Molecular Weight | 414.32 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Abiraterone Impurity 45 is closely related to a steroid core, a hydroxyl group, an ether linkage, iodine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
As a process- or degradation-related impurity, Abiraterone Impurity 45 (CAS CATO-C4X-107045, C19H27IO2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Abiraterone Impurity 45 (C19H27IO2) is characterized by a steroid core, a hydroxyl group, an ether linkage, iodine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Abiraterone Impurity 45 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C19H27IO2 |
| Molecular Weight | 414.32 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | I-containing |
Related Abiraterone Standards
- Abiraterone Impurity 44 (CAS CATO-C4X-107044)
- Abiraterone Impurity 64 (CAS CATO-C4X-107064)
- Abiraterone Acetate-d4 (CAS 2122245-63-8)
- Abiraterone Impurity 65 (CAS CATO-C4X-107065)
- Abiraterone Acetate N-Oxide (CAS 2517964-85-9)
- Abiraterone Impurity 10 (CAS CATO-C4X-107010)
- Abiraterone Impurity 11 (CAS CATO-C4X-107011)
- Abiraterone Impurity 4 (CAS 2484719-26-6)
Recommended Standards
- N-(4-((4-bromophenyl)thio)phenyl)-3-methoxybenzamide (CAS 339031-24-2)
- 1-(4-Cyano-3-(trifluoromethyl)phenyl)-3-(3-cyano-4-(trifluoromethyl)phenyl)thiourea (CAS 1415564-70-3)
- 2-[Difluoro-(3,4,5-trifluorophenoxy)Methyl]-5-(4-ethylphenyl)-1,3-difluoro-benzene (CAS 303186-19-8)
- (2R,4S)-ETHYL 5-(4-BROMOPHENYL)-4-(BOC-AMINO)-2-METHYLPENTANOATE (CAS 1931129-45-1)
- Tirofiban Impurity 47 (CAS CATO-C4X-125447)
- Rotigotine EP Impurity E HCl (CAS 2708278-88-8)
- Domperidone Impurity 40(1s,4r) (CAS CATO-C4X-142040)
- Dimethyl 1-(4-methoxyphenyl)-1H-1,2,3-triazole-4,5-dicarboxylate (CAS 4953-05-3)
- 3-Bromo-2-bromomethylpyridine, 97% (CAS 754131-60-7)
- Cyanomethyl (3,5-Dimethyl-1H-pyrazole)-carbodithioate (CAS 1823403-92-4)
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- Neuropeptide Y (3-36) (human, rat) trifluoroacetate salt (CAS 150138-78-6)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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