Rotigotine EP Impurity E HCl CAS 2708278-88-8
| CAS No. | 2708278-88-8 |
| Molecular Formula | C19H25NO2S |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 367.93 g/mol gives Rotigotine EP Impurity E HCl distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
As a process- or degradation-related impurity, Rotigotine EP Impurity E HCl (CAS 2708278-88-8, C19H25NO2SHCl) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C19H25NO2SHCl, Rotigotine EP Impurity E HCl contains a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 367.93 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Rotigotine EP Impurity E HCl under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C19H25NO2S HCl |
| Molecular Weight | 367.93 g/mol |
| Purity | >80% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2002 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Rotigotine Standards
- Rotigotine Impurity 11 (CAS 101403-24-1)
- Rotigotine impurity 23 (CAS 101470-23-9)
- Rotigotine EP Impurity B Hydrochloride (CAS 101470-23-9（free base）)
- Rotigotine Racemate HCl (CAS 102120-99-0)
- Rotigotine Impurity 40 (CAS 102121-00-6)
- Rotigotine EP Impurity A (CAS 112835-48-0)
- Rotigotine EP Impurity A HCl (CAS 112835-48-0（free base）)
- Rotigotine EP Impurity H (CAS 1148154-91-9)
Recommended Standards
- Tapentadol Impurity 14 (CAS CATO-C4X-209914)
- Goserelin EP Impurity K (CAS 1926163-83-8)
- Phenytoin Impurity 15 (CAS CATO-C4X-186415)
- 4-(((3-Methylthiophen-2-yl)methylene)amino)-3-(pyridin-2-yl)-1H-1,2,4-triazole-5(4H)-thione (CAS 613248-17-2)
- 1-(5-amino-4-chloro-2-methyl-phenyl)hexahydropyrimidine-2,4-dione (CAS 2703773-12-8)
- [2-(2-methoxyethoxy)-4-methylphenyl]methanamine (CAS 1249721-27-4)
- 3-Amino-5-iodobenzonitrile (CAS 49674-31-9)
- Ozefloxacin Impurity 18 (CAS 856836-09-4)
- 1-[(4-bromo-2-methylphenyl)carbonyl]piperidine-3-carboxylic acid (CAS 1156845-33-8)
- Semaglutide impurity 25 (CAS CATO-C4X-222625)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com