Axitinib Impurity 69 CAS CATO-C4X-107169
| CAS No. | CATO-C4X-107169 |
| Molecular Formula | C17H15N3O2S |
| Molecular Weight | 325.38 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a process- or degradation-related impurity, Axitinib Impurity 69 (CAS CATO-C4X-107169, C17H15N3O2S) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Axitinib Impurity 69 (C17H15N3O2S) contains a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 12.0, corresponding to approximately 12 ring(s) or double-bond equivalent(s). With a molecular weight of 325.38 g/mol, it falls into the moderately-high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C17H15N3O2S |
| Molecular Weight | 325.38 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Axitinib Standards
- Axitinib Impurity 40 (CAS CATO-C4X-107140)
- Axitinib Impurity 52 (CAS CATO-C4X-107152)
- Axitinib Impurity 23 (CAS CATO-C4X-107123)
- Axitinib Impurity N25 (CAS 1266386-30-4)
- Axitinib Impurity 73 (CAS CATO-C4X-107173)
- Axitinib Impurity 14 (CAS 886230-76-8)
- Axitinib Impurity 19 (CAS CATO-C4X-107119)
- Axitinib Impurity 15 (CAS CATO-C4X-107115)
Recommended Standards
- Faropenem Impurity 10 (CAS 106559-80-2)
- 7977FZ765Q 592-87-0 Lead thiocyanate Lead(II) thiocyanate Lead dithiocyanate Thiocyanic acid, lead(2+) salt (2:1) Thiocyanic acid, lead(2+) salt EINECS 209-774-6 HSDB 641 Isothiocyanic acid, lead(2+) salt Lead isothiocyanate Lead sulfocyanate Lead thiocyanate (Pb(SCN)2) Lead(II) thiocyanate (Pb(NCS)2) UNII-7977FZ765Q (CAS 592-87-0)
- Flumazenil Impurity 16 (CAS CATO-C4X-143216)
- Phenyl(1-tosyl-1H-pyrrol-2-yl)methanone (CAS 827024-03-3)
- Galanthamine Impurity 37 (CAS CATO-C4X-143537)
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- Cefminox Impurity 4 (CAS CATO-C4X-19264)
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- 1-(Furan-2-ylmethyl)-1,3-dihydro-2H-imidazole-2-thione (CAS 113825-02-8)
- 1-(2,4-Dichloropyrimidin-5-yl)ethan-1-ol (CAS 130825-17-1)
- Rel-(3S,5R)-3,5-dimethyl-1-(naphthalen-2-ylsulfonyl)piperazine (CAS 1187929-41-4)
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