Flumazenil Impurity 16 CAS CATO-C4X-143216
| CAS No. | CATO-C4X-143216 |
| Molecular Formula | C19H20FN3O |
| Molecular Weight | 325.38 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO supplies Flumazenil Impurity 16 (CAS CATO-C4X-143216), a pharmacopoeial impurity reference standard (molecular formula C19H20FN3O, MW 325.38 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, Flumazenil Impurity 16 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 325.38 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C19H20FN3O |
| Molecular Weight | 325.38 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Flumazenil Standards
- Flumazenil Impurity 18 (CAS CATO-C4X-143218)
- Flumazenil EP Impurity F (CAS 78756-33-9)
- Flumazenil Impurity 15 (CAS CATO-C4X-143215)
- Flumazenil Impurity 17 (CAS CATO-C4X-143217)
- Flumazenil-D5 (CAS 2700278-14-2)
- Flumazenil (CAS 78755-81-4)
- Flumazenil Impurity 12 (CAS CATO-C4X-143212)
- Flumazenil EP Impurity B (CAS 131666-45-0)
Recommended Standards
- Faropenem Impurity 10 (CAS 106559-80-2)
- Lesinurad Impurity 14 (CAS 1533519-93-5)
- Axitinib Impurity 69 (CAS CATO-C4X-107169)
- Lesinurad Impurity 7 (CAS CATO-C4X-14787)
- Milrinone impurity 38 (CAS CATO-C4X-109138)
- Osimertinib Impurity 32 (CAS CATO-C4X-204532)
- Benzalkonium Chloride impurity 5 (CAS 41961-81-3)
- 5-{2-[(6-chloroquinolin-4-yl)methyl]-7-(cyclopropylmethyl)-5-methyl-4,6-dioxo-2H,4H,5H,6H,7H-pyrazolo[3,4-d]pyrimidin-3-yl}-1-methyl-1H-pyrrole-3-carbonitrile (CAS 946411-72-9)
- 2-((5-(4-Chlorophenyl)-2,2-dimethyl-2H-imidazol-4-yl)thio)-N-phenylacetamide (CAS 899906-56-0)
- 2-((Cyclopropyl(pyrazin-2-yl)methyl)amino)ethanol (CAS 1248020-18-9)
- 4-((2-Hydroxy-5-methylphenyl)amino)-4-oxobutanoic acid (CAS 249277-56-3)
- Ethyl (3E)-3-(isopropylimino)-2-oxopropanoate (CAS 1086375-87-2)
- 4,4-Azodianiline (CAS 538-41-0)
- Semaglutide Impurity 82 (CAS CATO-C4X-222682)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com