Bortezomib Impurity 46 CAS CATO-C4X-107246
| CAS No. | CATO-C4X-107246 |
| Molecular Formula | C84H96B3N15O12 |
| Molecular Weight | 1540.19 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Bortezomib Impurity 46 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
As a process- or degradation-related impurity, Bortezomib Impurity 46 (CAS CATO-C4X-107246, C84H96B3N15O12) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Bortezomib Impurity 46 (C84H96B3N15O12) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C84H96B3N15O12 |
| Molecular Weight | 1540.19 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 44.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 15 |
Related Bortezomib Standards
- Bortezomib(Trimeric Boroxine Form) (CAS 390800-88-1)
- Bortezomib Impurity 47（1S,2R） (CAS CATO-C4X-107247)
- Bortezomib Impurity 48（1R,2R） (CAS CATO-C4X-107248)
- Bortezomib Impurity 60 (CAS CATO-C4X-107260)
- Bortezomib Impurity 63 (CAS 1375004-38-8)
- Bortezomib Impurity 24 (CAS CATO-C4X-107224)
- Bortezomib Impurity 59 (CAS CATO-C4X-107259)
- Bortezomib Impurity 18 (CAS CATO-C4X-107218)
Recommended Standards
- Indocyanine Green Impurity 66 (CAS CATO-C4X-250366)
- (12E,14E,21E)-2,3,9,10,16,17,23,24-octakis(octyloxy)-13H,29H-phthalocyanine (CAS 119457-81-7)
- PYX-1 (H-5786.0500) (CAS 140842-17-7)
- Carboxymethyl-β-Cyclodextrin (CAS 218269-34-2)
- Posaconazole Impurity 99 (CAS CATO-C4X-1208199)
- Landiolol Impurity 141 (CAS CATO-C4X-2621141)
- Olanzapine Impurity 66 (CAS CATO-C4X-117866)
- (S)-3-(Aminomethyl)-4-chloro-7-(2-hydroxyethoxy)benzo[c][1,2]oxaborol-1(3H)-ol hydrochloride (CAS 2131798-13-3)
- Boc-(+/-)-trans-4-(2-methoxyphenyl)pyrrolidine-3-carboxylic acid (CAS 1217689-78-5)
- 3-Methylisoxazolo[4,5-b]pyrazine (CAS 41230-53-9)
- Tert-butyl 4-(4-amino-2-iodo-5-isopropoxyphenyl)piperidine-1-carboxylate (CAS 2306262-70-2)
- 1-Formylethylidenetriphenylphosphorane 2-(Triphenylphosphoranylidene)propionaldehyde 24720-64-7 (CAS 24720-64-7)
- (2,3-Difluoro-4-hexylphenyl)boronic acid (CAS 156684-87-6)
- Semaglutide impurity 199 (CAS CATO-C4X-2226199)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com