Bortezomib Impurity 37 CAS CATO-C4X-107237
| CAS No. | CATO-C4X-107237 |
| Molecular Formula | C19H25BN4O5 |
| Molecular Weight | 400.24 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
CATO supplies Bortezomib Impurity 37 (CAS CATO-C4X-107237), a pharmacopoeial impurity reference standard (molecular formula C19H25BN4O5, MW 400.24 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, Bortezomib Impurity 37 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 400.24 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C19H25BN4O5 |
| Molecular Weight | 400.24 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 9.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 4 |
Related Bortezomib Standards
- Bortezomib Impurity 50 (CAS CATO-C4X-107250)
- Bortezomib Impurity N47 (CAS 514820-48-5)
- Bortezomib (CAS 179324-69-7)
- Bortezomib Impurity 35 (CAS 1104011-35-9)
- Bortezomib Impurity 5 (CAS 1132709-16-0)
- Bortezomib Impurity 6 (CAS 1132709-14-8)
- Bortezomib Impurity 7 (CAS 1132709-15-9)
- Bortezomib Impurity 51 (CAS 1194235-14-7)
Recommended Standards
- 6-Bromo-1,4-dihydro-7-fluoro-1-[(1S)-1-(hydroxymethyl)-2-methylpropyl]-4-oxo-3-quinolinecarboxylic Acid Ethyl Ester (CAS 934161-50-9)
- 4-(5-Bromo-2-ethoxybenzenesulfonamido)benzoic acid (CAS 327086-78-2)
- Apalutamide Impurity 23 (CAS CATO-C4X-274923)
- 3-(3-Bromo-4-ethoxy-phenylsulfamoyl)-benzoic acid (CAS 519152-84-2)
- Azilsartan Impurity 2 (CAS 1403474-76-9)
- Landiolol Impurity 5 HCl (CAS CATO-C4X-26215)
- N-Nitroso Cinacalcet Impurity 5 (CAS CATO-C4X-105976)
- N-(2-methoxyethyl)-N-methylpiperidine-3-sulfonamide (CAS 1249825-79-3)
- 3-BRomo-4-methoxyphenyl acetate (CAS 124764-37-0)
- N-phenylnaphthalen-1-amine hydrobromide (CAS 205526-65-4)
- tert-butyl (5R)-5-ethyl-2,2-dioxo-oxathiazolidine-3-carboxylate (CAS 2382671-84-1)
- 4,4'-(2-(4-Aminostyryl)oxazole-4,5-diyl)dianiline (CAS 110007-74-4)
- 3-[4-(2,3-dimethylphenyl)piperazine-1-carbonyl]-N,N-dimethyl-4-(pyrrolidin-1-yl)benzene-1-sulfonamide (CAS 794572-10-4)
- Neuropeptide Y (1-24) amide (human, rat) (CAS 131448-51-6)
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