Tenofovir Impurity 34 CAS CATO-C4X-107634
| CAS No. | CATO-C4X-107634 |
| Molecular Formula | C59H90N15O30P3 |
| Molecular Weight | 1582.35 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Tenofovir Impurity 34 (C59H90N15O30P3) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a phosphate ester group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a process- or degradation-related impurity, Tenofovir Impurity 34 (CAS CATO-C4X-107634, C59H90N15O30P3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C59H90N15O30P3 |
| Molecular Weight | 1582.35 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 22.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 15 |
Related Tenofovir Standards
- Tenofovir disoproxil Impurity 112 (CAS CATO-C4X-1076112)
- Tenofovir Trimer Impurity 51 (CAS CATO-C4X-107651)
- Tenofovir disoproxil Impurity 33 (CAS CATO-C4X-107633)
- Tenofovir Trimer Impurity 52 (CAS CATO-C4X-107652)
- Tenofovir Trimer Impurity 53 (CAS CATO-C4X-107653)
- Tenofovir disoproxil Impurity 128 (CAS CATO-C4X-1076128)
- Tenofovir disoproxil Impurity 132 (CAS CATO-C4X-1076132)
- Tenofovir disoproxil Impurity 116 (CAS 2241284-68-2)
Recommended Standards
- [Ac-Ser1-Asp15-OH]-Thymalfasin (CAS CATO-C4X-189816)
- Moenomycin A (CAS 76095-39-1)
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- H-Lys-Lys-Glu-Asp-Val-Val-Abu-Cys-Ser-Abu-Ser-Tyr-Lys-Lys-NH2 (M-2095.0001) (CAS 396096-62-1)
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