Tofacitinib Impurity 235 CAS CATO-C4X-1079235
| CAS No. | CATO-C4X-1079235 |
| Molecular Formula | C15H16N6O |
| Molecular Weight | 296.33 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Tofacitinib Impurity 235 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Tofacitinib Impurity 235 (CAS CATO-C4X-1079235) is a certified pharmaceutical impurity reference standard with the molecular formula C15H16N6O and a molecular weight of 296.33 g/mol.
Based on its molecular formula C15H16N6O, Tofacitinib Impurity 235 contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 296.33 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C15H16N6O |
| Molecular Weight | 296.33 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | ≥95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 6 |
Related Tofacitinib Standards
- Tofacitinib Impurity 129 (CAS 1527525-58-1)
- Tofacitinib Impurity 247 (CAS CATO-C4X-1079247)
- Tofacitinib Impurity 30 (CAS CATO-C4X-107930)
- Tofacitinib Nitroso Impurity 191 (CAS CATO-C4X-1079191)
- Tofacitinib Impurity 204 (CAS CATO-C4X-1079204)
- Tofacitinib Impurity 176 (CAS CATO-C4X-1079176)
- Tofacitinib Impurity 59 (CAS 2250241-69-9)
- Tofacitinib Impurity 160 (CAS CATO-C4X-1079160)
Recommended Standards
- tert-Butyl 4-(dimethylamino)-4-(trifluoromethyl)piperidine-1-carboxylate (CAS 2227206-58-6)
- N-(4-Carbamoylphenyl)benzo[b]thiophene-2-carboxamide (CAS 1011435-42-9)
- Tert-butyl 3-(dimethylamino)-3-(trifluoromethyl)piperidine-1-carboxylate (CAS 2306274-78-0)
- Tert-butyl 3-[(4-fluoro-2-methylphenyl)amino]-3-oxopropylcarbamate (CAS 1016698-11-5)
- Cefamandole Open-Ring Impurity (CAS CATO-C4X-122127)
- Trimethoprim EP Impurity C (CAS 29606-06-2)
- Dasatinib impurity 61 (CAS CATO-C4X-160761)
- Methyl 2-fluoro-3,3,3-trimethoxypropanoate (CAS 77778-66-6)
- (2E)-1-(2,4-Dimethoxyphenyl)-3-(4-ethylphenyl)prop-2-en-1-one (CAS 786699-15-8)
- 2-Isopropylisonicotinohydrazide (CAS 113548-81-5)
- 1-(5-Methylisoxazol-3-yl)cyclopentane-1-carboxylic acid (CAS 1352534-04-3)
- 4-Bromo-2-(2-methoxypyridin-3-yl)thiazole (CAS 1415562-60-5)
- 2-Bromo-3-(chloromethyl)-4-(difluoromethyl)pyridine (CAS 1806770-59-1)
- Semaglutide Impurity 142 (CAS CATO-C4X-2226142)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com