Levocetirizine Impurity 73 CAS CATO-C4X-108373
| CAS No. | CATO-C4X-108373 |
| Molecular Formula | C29H40ClN2O6 |
| Molecular Weight | 548.09 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO supplies Levocetirizine Impurity 73 (CAS CATO-C4X-108373), a pharmacopoeial impurity reference standard (molecular formula C29H40ClN2O6, MW 548.09 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Levocetirizine Impurity 73 (C29H40ClN2O6) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C29H40ClN2O6 |
| Molecular Weight | 548.09 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | ≥95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Levocetirizine Standards
- Levocetirizine Impurity 72 (CAS CATO-C4X-108372)
- Levocetirizine Impurity 71 (CAS CATO-C4X-108371)
- Levocetirizine Impurity 78 (CAS CATO-C4X-108378)
- Levocetirizine Impurity 58 (CAS CATO-C4X-108358)
- Levocetirizine Impurity 45 (CAS 1150310-68-1)
- Levocetirizine Impurity 64 (CAS CATO-C4X-108364)
- Levocetirizine Impurity 47 (CAS CATO-C4X-108347)
- Levocetirizine Impurity 19 (CAS CATO-C4X-108319)
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