Ambroxol impurity 05 CAS CATO-C4X-1085105
| CAS No. | CATO-C4X-1085105 |
| Molecular Formula | C14H17Br2N3O2 |
| Molecular Weight | 419.11 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Ambroxol impurity 05 (C14H17Br2N3O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, bromine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO supplies Ambroxol impurity 05 (CAS CATO-C4X-1085105), a pharmacopoeial impurity reference standard (molecular formula C14H17Br2N3O2, MW 419.11 g/mol) used for the identification and quantification of trace impurities in APIs.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Ambroxol impurity 05 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C14H17Br2N3O2 |
| Molecular Weight | 419.11 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 3 |
Related Ambroxol Standards
- Ambroxol Impurity 93 (CAS CATO-C4X-108593)
- Ambroxol Impurity 96 (CAS CATO-C4X-108596)
- Ambroxol-D4 N-nitroso (CAS CATO-C4X-1085111)
- Ambroxol Impurity 52 (CAS CATO-C4X-108552)
- Ambroxol impurity 112 (CAS CATO-C4X-1085112)
- Ambroxol Impurity 57 (CAS CATO-C4X-108557)
- Ambroxol Impurity 94 (CAS CATO-C4X-108594)
- Ambroxol Impurity 59 (CAS 2376577-10-3)
Recommended Standards
- 9,11-Dibromo-3-methoxy-5,6-dihydrobenzo[c]acridine (CAS 866040-73-5)
- 2,4-Dibromo-9-methoxy-10,11-dihydro-5-azatetraphene (CAS 865658-91-9)
- cis-(1,2-Diamino-4-nitrobenzene)dichloroplatinum(II) (CAS 72596-02-2)
- 2,2'-(Bromomethylene)bis(1-fluoro-4-(trifluoromethyl)benzene) (CAS 2149590-94-1)
- Sofosbuvir Impurity 55 (CAS CATO-C4X-105255)
- Chlorhexidine EP Impurity A Hydrochloride (CAS 152504-08-0（free base）)
- Ibrutinib Impurity 174 (CAS CATO-C4X-1064174)
- 2-(2-Methoxypyridin-3-yl)acetonitrile (CAS 351410-37-2)
- 2-(2-(3-Amino-4-methyl-1h-pyrazol-1-yl)ethoxy)ethan-1-ol (CAS 1340100-32-4)
- (5Z)-5-{[3-(4-Fluorophenyl)-1-phenyl-1H-pyrazol-4-yl]methylidene}-3-(3-methoxypropyl)-2-thioxo-1,3-thiazolidin-4-one (CAS 313273-20-0)
- 2-(3-Chloro-4-(trifluoromethyl)pyridin-2-yl)ethan-1-amine (CAS 1393561-19-7)
- (+)-Bicifadine Hydrochloride (1R,5S)-1-(4-Methylphenyl)-3-azabicyclo[3.1.0]hexane Hydrochloride 66504-82-3 (CAS 66504-82-3)
- 2-{2-[4-(tert-Butyl)phenyl]hydrazono}-2-(tert-butylsulfonyl)acetonitrile (CAS 241127-22-0)
- Semaglutide Impurity 115 (CAS CATO-C4X-2226115)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com