Ambroxol Maillard Lactose Impurity 1(Ambroxol Impurity 70) CAS CATO-C4X-108570
| CAS No. | CATO-C4X-108570 |
| Molecular Formula | C18H26Br2N2O5 |
| Molecular Weight | 510.22 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
CATO supplies Ambroxol Maillard Lactose Impurity 1(Ambroxol Impurity 70) (CAS CATO-C4X-108570), a pharmacopoeial impurity reference standard (molecular formula C18H26Br2N2O5, MW 510.22 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Ambroxol Maillard Lactose Impurity 1(Ambroxol Impurity 70) (C18H26Br2N2O5) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C18H26Br2N2O5 |
| Molecular Weight | 510.22 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >90% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 2 |
Related Ambroxol Standards
- Ambroxol Maillard Lactose Impurity 2(Ambroxol Impurity 71) (CAS CATO-C4X-108571)
- Ambroxol Maillard Lactose Impurity 3(Ambroxol Impurity 72) (CAS CATO-C4X-108572)
- Ambroxol Maillard Lactose Impurity 4(Ambroxol Impurity 73) (CAS CATO-C4X-108573)
- Ambroxol Maillard Lactose Impurity 7(Ambroxol Impurity 76) (CAS CATO-C4X-108576)
- Ambroxol Maillard Lactose Impurity 8(Ambroxol Impurity 77) (CAS CATO-C4X-108577)
- Ambroxol Impurity 41 (CAS CATO-C4X-108541)
- Ambroxol Sorbide Impurity 3(Ambroxol Impurity 79) (CAS CATO-C4X-108579)
- Ambroxol Impurity 95 (CAS CATO-C4X-108595)
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Why CATO?
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