Ambroxol Maillard Lactose Impurity 2(Ambroxol Impurity 71) CAS CATO-C4X-108571
| CAS No. | CATO-C4X-108571 |
| Molecular Formula | C18H26Br2N2O5 |
| Molecular Weight | 510.22 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
As a process- or degradation-related impurity, Ambroxol Maillard Lactose Impurity 2(Ambroxol Impurity 71) (CAS CATO-C4X-108571, C18H26Br2N2O5) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Ambroxol Maillard Lactose Impurity 2(Ambroxol Impurity 71) (C18H26Br2N2O5) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, bromine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C18H26Br2N2O5 |
| Molecular Weight | 510.22 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >90% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 2 |
Related Ambroxol Standards
- Ambroxol Maillard Lactose Impurity 1(Ambroxol Impurity 70) (CAS CATO-C4X-108570)
- Ambroxol Maillard Lactose Impurity 3(Ambroxol Impurity 72) (CAS CATO-C4X-108572)
- Ambroxol Maillard Lactose Impurity 4(Ambroxol Impurity 73) (CAS CATO-C4X-108573)
- Ambroxol Maillard Lactose Impurity 7(Ambroxol Impurity 76) (CAS CATO-C4X-108576)
- Ambroxol Maillard Lactose Impurity 8(Ambroxol Impurity 77) (CAS CATO-C4X-108577)
- Ambroxol Impurity 41 (CAS CATO-C4X-108541)
- Ambroxol Sorbide Impurity 3(Ambroxol Impurity 79) (CAS CATO-C4X-108579)
- Ambroxol Impurity 95 (CAS CATO-C4X-108595)
Recommended Standards
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- 6,6'-Dimethyl 5,5'-dibromo-2H,2'H,3H,3'H-[1,1'-biindole]-6,6'-dicarboxylate (CAS 2007910-50-9)
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