Apixaban Impurity 68 CAS CATO-C4X-108868
| CAS No. | CATO-C4X-108868 |
| Molecular Formula | C24H21ClN4O4 |
| Molecular Weight | 464.90 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Apixaban Impurity 68 (CAS CATO-C4X-108868) is a certified pharmaceutical impurity reference standard with the molecular formula C24H21ClN4O4 and a molecular weight of 464.90 g/mol.
Owing to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, Apixaban Impurity 68 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 464.90 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO manufactures Apixaban Impurity 68 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C24H21ClN4O4 |
| Molecular Weight | 464.90 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
Related Apixaban Standards
- Apixaban Impurity 154 (CAS CATO-C4X-1088154)
- Apixaban Impurity 156 (CAS CATO-C4X-1088156)
- Apixaban Impurity 5 (CAS 2029205-64-7)
- Apixaban-13C，d3 (CAS 1261393-15-0)
- Apixaban Impurity 86 (CAS CATO-C4X-108886)
- Apixaban Impurity 108 (CAS CATO-C4X-1088108)
- Apixaban-d3 (CAS 1131996-12-7)
- Apixaban Impurity 1 (CAS 503614-92-4)
Recommended Standards
- Methyl 3-(4-{[(4-chlorophenyl)carbamoyl]oxy}phenyl)-2-(1-oxo-2,3-dihydro-1H-isoindol-2-yl)propanoate (CAS 477889-60-4)
- 4-Chloro-N,N-bis(4-methoxybenzyl)-3,6-dimethyl-5-(trifluoromethyl)pyridin-2-amine (CAS 2852767-64-5)
- N-Tritriacontane (CAS 630-05-7)
- 6-Chloro-N,N-bis(4-methoxybenzyl)-4-methyl-5-(2,2,2-trifluoroethyl)pyridin-2-amine (CAS 2852767-00-9)
- Cabozantinib Impurity 43 (CAS CATO-C4X-201843)
- Nemonoxacin Impurity 65 (CAS CATO-C4X-312865)
- Pimavanserin Impurity 30 (CAS 359878-47-0（free base）)
- 6-(((Bis(2-cyanoethoxy)phosphoryl)oxy)methyl)-2,2-dimethyltetrahydro-4H-furo[3,2-d][1,3]dioxin-7-yl acetate (CAS 1041021-85-5)
- 326495-41-4 2-Azaniumylethyl (2R)-2,3-bis[(~2~H_27_)tetradecanoyloxy]propyl phosphate DTXSID80677037 (CAS 326495-41-4)
- (Z)-2-amino-N'-hydroxy-5-nitrobenzimidamide (CAS 60024-27-3)
- 2,2'-(1,4-Phenylenebis(methaneylylidene))dimalononitrile (CAS 17239-69-9)
- 3-(Cyclohexyloxy)-5-nitro-1H-indazole (CAS 1365942-70-6)
- (3-Chloro-2-methylpropyl)benzene (CAS 73756-58-8)
- Lixisenatide (CAS 320367-13-3（free base）)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com