Dabigatran Impurity 12 CAS CATO-C4X-108912
| CAS No. | CATO-C4X-108912 |
| Molecular Formula | C26H25N7O5 |
| Molecular Weight | 515.52 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Dabigatran Impurity 12 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Dabigatran Impurity 12 (CAS CATO-C4X-108912) is a certified pharmaceutical impurity reference standard with the molecular formula C26H25N7O5 and a molecular weight of 515.52 g/mol.
The molecular framework of Dabigatran Impurity 12 (C26H25N7O5) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C26H25N7O5 |
| Molecular Weight | 515.52 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 18.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 7 |
Related Dabigatran Standards
- Dabigatran Isopropyl Ester Impurity (CAS 1610758-17-2)
- Dabigatran Impurity 120 (CAS CATO-C4X-1089120)
- Dabigatran Impurity 122 (CAS CATO-C4X-1089122)
- Dabigatran Impurity 90 (CAS 1354892-78-6)
- Dabigatran Impurity 117 (CAS CATO-C4X-1089117)
- Dabigatran Impurity 118 (CAS CATO-C4X-1089118)
- Dabigatran Impurity 79 (CAS 1422495-93-9)
- Dabigatran Impurity 30 (CAS 948551-71-1)
Recommended Standards
- Ethyl 7-(3,4-dimethoxyphenyl)-2-methyl-5-oxo-4-(4-(trifluoromethyl)phenyl)-1,4,5,6,7,8-hexahydroquinoline-3-carboxylate (CAS 333308-93-3)
- Minocycline Impurity 43 (CAS 28698-94-4)
- Doxorubicin Impurity 32 (CAS CATO-C4X-203332)
- Pemetrexed Impurity 55 (CAS CATO-C4X-172655)
- Zolmitriptan Impurity 35 (Mixture of Diastereomers) (CAS CATO-C4X-135135)
- Sitagliptin Impurity 53 HCl (CAS 849832-76-4(free base))
- Melatonin EP Impurity B (CAS 1210-83-9)
- Mono(2-ethyl-5-oxohexyl) Adipate-d4 (CAS CATO-CCHM706083)
- 2,3-dihydropyrano[2,3-b]pyridin-4-one (CAS 1196153-27-1)
- Isopropyl 2-(3-amino-2-oxopyridin-1(2h)-yl)acetate (CAS 1249626-81-0)
- Ethyl (4aS,8aR)-2-thioxooctahydro-1,6-naphthyridine-6(2H)-carboxylate (CAS 1890136-14-7)
- 1-(6-Chloro-5-fluoropyridin-3-yl)ethanone (CAS 1256824-98-2)
- 5-Isopropyl-1-(pyridin-2-yl)-1h-pyrazole-3-carboxylic acid (CAS 1177330-29-8)
- Ginseng Tetrapeptide (CAS 178553-95-2)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com