Rivaroxaban Impurity 109 HCl CAS CATO-C4X-1090109
| CAS No. | CATO-C4X-1090109 |
| Molecular Formula | C15H22N4O4 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Rivaroxaban Impurity 109 HCl (C15H22N4O4HCl) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a process- or degradation-related impurity, Rivaroxaban Impurity 109 HCl (CAS CATO-C4X-1090109, C15H22N4O4HCl) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Rivaroxaban Impurity 109 HCl under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C15H22N4O4 HCl |
| Molecular Weight | 358.82 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
Related Rivaroxaban Standards
- Rivaroxaban Impurity 96 (CAS 1007650-38-5)
- Rivaroxaban Impurity 57 (CAS 1082495-22-4)
- Rivaroxaban Impurity 47 (CAS 1082588-73-5)
- Rivaroxaban-d4 (CAS 1132681-38-9)
- Rivaroxaban Impurity 74 (CAS 113471-08-2)
- Rivaroxaban EP Impurity I (CAS 1151893-81-0)
- Rivaroxaban 3-Hydroxy Metabolite (CAS 1159977-46-4)
- Rivaroxaban Impurity 15 (Mixture of Diastereomers) (CAS 1160169-99-2)
Recommended Standards
- Sitagliptin Impurity 37 (CAS 486459-98-7)
- (R)-Olodaterol Benzyl Ether (CAS 869478-13-7)
- Atrasentan Impurity 146 (CAS 1058350-25-6)
- 2-Fluoro-5-(3-fluorobenzyl)benzonitrile (CAS 1108745-28-3)
- [(Z)-2-(2-Chloro-1,3-thiazol-5-yl)-2-(4-methylbenzenesulfonyl)ethenyl]dimethylamine (CAS 478043-87-7)
- Cyclopropylmethyl 5,6-dichloropyridine-3-carboxylate (CAS 1340556-60-6)
- N-Nitroso-Desmethyl-Bedaquiline-D3(Mixture of Entiomers) (CAS CATO-C4X-116755)
- Isobutyl 3-hydroxybenzoate (CAS 63638-02-8)
- 3-(3,5-Dichloro-4-fluorophenyl)-5,5-dimethylimidazolidine-2,4-dione (CAS 66654-62-4)
- Des-Lys16-Tirzepatide (CAS CATO-CPTD788957)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com