Rivaroxaban Impurity 47 CAS 1082588-73-5
| CAS No. | 1082588-73-5 |
| Molecular Formula | C10H12N2O2 |
| Molecular Weight | 192.21 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Rivaroxaban Impurity 47.
CATO supplies Rivaroxaban Impurity 47 (CAS 1082588-73-5), a pharmacopoeial impurity reference standard (molecular formula C10H12N2O2, MW 192.21 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, Rivaroxaban Impurity 47 (C10H12N2O2) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 6.0, corresponding to approximately 6 ring(s) or double-bond equivalent(s). With a molecular weight of 192.21 g/mol, it falls into the medium-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Rivaroxaban Impurity 47 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H12N2O2 |
| Molecular Weight | 192.21 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Nitrogen Atoms | 2 |
Related Rivaroxaban Standards
- Rivaroxaban Impurity 87 (CAS 96800-35-0)
- Rivaroxaban impurity 193 (CAS CATO-C4X-1090193)
- Rivaroxaban Impurity 32 (CAS 438056-69-0)
- Rivaroxaban Impurity 57 (CAS 1082495-22-4)
- Rivaroxaban Impurity 83 (CAS 1456733-00-8)
- Rivaroxaban Impurity N1 (CAS 88777-57-5)
- Rivaroxaban Impurity 96 (CAS 1007650-38-5)
- Rivaroxaban Impurity 97 (CAS 2288308-42-7)
Recommended Standards
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- Amisulpride Impurity 37 (CAS 27492-84-8)
- Irbesartan Impurity 47 (CAS CATO-C4X-166647)
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- (Z)-2-(2,2-dimethylpropanoyl)-3-[4-(2-fluorophenyl)piperazino]-2-propenenitrile (CAS 1025124-66-6)
- (2R,3R,4S,5R)-2-(6-Amino-8-vinyl-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol (CAS 142386-40-1)
- Manganese perchlorate hexahydrate (CAS 15364-94-0)
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- Glucagon (1-29) (CAS 16941-32-5)
Why CATO?
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