Rivaroxaban Impurity 160 CAS CATO-C4X-1090160
| CAS No. | CATO-C4X-1090160 |
| Molecular Formula | C21H20N4O6 |
| Molecular Weight | 424.41 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Rivaroxaban Impurity 160.
Rivaroxaban Impurity 160 (CAS CATO-C4X-1090160) is a certified pharmaceutical impurity reference standard with the molecular formula C21H20N4O6 and a molecular weight of 424.41 g/mol.
Owing to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, Rivaroxaban Impurity 160 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 424.41 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C21H20N4O6 |
| Molecular Weight | 424.41 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 4 |
Related Rivaroxaban Standards
- Rivaroxaban impurity 167 (CAS CATO-C4X-1090167)
- Rivaroxaban Impurity 177 (CAS CATO-C4X-1090177)
- Rivaroxaban Impurity 183 (CAS CATO-C4X-1090183)
- Rivaroxaban Impurity 186 (CAS CATO-C4X-1090186)
- Rivaroxaban Impurity 100 (CAS CATO-C4X-1090100)
- Rivaroxaban Impurity 104（Enantiomer Mixture） (CAS 1265617-06-8)
- Rivaroxaban Impurity 31 (CAS 1424944-35-3)
- Rivaroxaban EP Impurity G (CAS 446292-08-6)
Recommended Standards
- Ethyl 2-((4-fluorobenzyl)(4-(trifluoromethyl)phenyl)amino)thiazole-4-carboxylate (CAS 860783-96-6)
- 3-{[(4-chlorophenyl)methyl]sulfanyl}-5-({[(4-chlorophenyl)methyl]sulfanyl}methyl)-4-ethyl-4H-1,2,4-triazole (CAS 344268-69-5)
- 3,3'-Dihydroxy-1H,1'H-[2,2'-biindole]-5,5'-disulfonic acid (CAS 28286-71-7)
- (2R,3S,4R,5R)-2-(Hydroxymethyl)-5-(6-(methylamino)-2-(4-(pyridin-2-yl)-1H-pyrazol-1-yl)-9H-purin-9-yl)tetrahydrofuran-3,4-diol (CAS 765299-61-4)
- Zolpidem Impurity 1 (CAS 109461-64-5)
- Pemafibrate Impurity 9 (CAS CATO-C4X-29039)
- Gefitinib Impurity 33 (CAS 909863-33-8)
- 2-(2,4-Dichlorobenzyl)pyrrolidine (CAS 383127-58-0)
- 3-(2-(Methyl(propyl)amino)ethyl)thietane 1,1-dioxide (CAS 1876537-97-1)
- 2,4-Dichloro-6-methylquinoline-3-carbonitrile (CAS 749865-98-3)
- 5-Bromo-4,6-dimethyl-2(1H)-pyrimidinone (CAS 7781-20-6)
- Lisinopril Impurity 25 (CAS 199002-00-1)
- 2-(Trifluoromethyl)piperidin-4-ol, mixture of diastereomers (CAS 1245644-81-8)
- D-[Phe]6-Liraglutide (CAS CATO-C4X-199235)
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