Ticagrelor impurity 167 CAS CATO-C4X-1093167
| CAS No. | CATO-C4X-1093167 |
| Molecular Formula | C14H22ClN5O6S |
| Molecular Weight | 423.87 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a process- or degradation-related impurity, Ticagrelor impurity 167 (CAS CATO-C4X-1093167, C14H22ClN5O6S) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution, Ticagrelor impurity 167 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 423.87 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), Ticagrelor impurity 167 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C14H22ClN5O6S |
| Molecular Weight | 423.87 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 5 |
| Sulfur Atoms | 1 |
Related Ticagrelor Standards
- Ticagrelor impurity 103 (CAS CATO-C4X-1093103)
- Ticagrelor Impurity 148 (CAS CATO-C4X-1093148)
- Ticagrelor Impurity 45 (CAS CATO-C4X-109345)
- Ticagrelor Impurity 47 (CAS 376608-74-1)
- Ticagrelor Impurity 32 (CAS 376608-75-2)
- Ticagrelor Impurity 52 (CAS CATO-C4X-109352)
- Ticagrelor Impurity 119 (CAS CATO-C4X-1093119)
- Ticagrelor Impurity 76 (Mixture of Diastereomers) (CAS CATO-C4X-109376)
Recommended Standards
- 4-[4-(Pyridin-2-yl)pyrimidin-2-yl]phenyl 4-chlorobenzene-1-sulfonate (CAS 477857-48-0)
- 2-(Tribromomethyl)quinoline-6-carboxylic acid (CAS 457068-83-6)
- Flumiclorac-Pentyl (CAS 87546-18-7)
- 1-(2-(4-Benzylphenoxy)ethyl)pyrrolidine (CAS 147664-41-3)
- Silodosin Impurity 31 (CAS CATO-C4X-175431)
- Venlafaxine Impurity 27 (CAS 940297-06-3)
- Miglitol Impurity 14 (CAS CATO-C4X-169714)
- (4-((Trifluoromethyl)sulfonyl)phenyl)methanol (CAS 219872-98-7)
- N-(1-(1H-benzo[d][1,2,3]triazol-1-yl)-2-methylpropyl)benzamide (CAS 117067-46-6)
- N1-(2-Cyclohexyl-2-hydroxyethyl)-N2-(thiophen-2-ylmethyl)oxalamide (CAS 1351594-55-2)
- 3-(2,4,6,7-Tetrahydropyrano[4,3-c]pyrazol-3-yl)aniline (CAS 2138127-67-8)
- 4-[(3,4-Difluorophenyl)(methylsulfonyl)amino]butanoic acid (CAS 1858251-12-3)
- 2-CYANOPHENYLBORONIC ACID NEOPENTYL ESTER (CAS 214360-47-1)
- Tirzepatide Impurity 35 (CAS CATO-C4X-324035)
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