Lenvatinib Impurity 145 CAS CATO-C4X-1140145
| CAS No. | CATO-C4X-1140145 |
| Molecular Formula | C25H24ClN5O5 |
| Molecular Weight | 509.94 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Based on its molecular formula C25H24ClN5O5, Lenvatinib Impurity 145 contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 509.94 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Lenvatinib Impurity 145 (CAS CATO-C4X-1140145) is a certified pharmaceutical impurity reference standard with the molecular formula C25H24ClN5O5 and a molecular weight of 509.94 g/mol.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Lenvatinib Impurity 145 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C25H24ClN5O5 |
| Molecular Weight | 509.94 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 5 |
Related Lenvatinib Standards
- Lenvatinib Impurity 184 (CAS 2412398-76-4)
- Lenvatinib Impurity 93 (CAS CATO-C4X-114093)
- Lenvatinib Impurity 88 (CAS CATO-C4X-114088)
- Lenvatinib Impurity 158 (CAS CATO-C4X-1140158)
- Lenvatinib Impurity 181 (CAS CATO-C4X-1140181)
- Lenvatinib Impurity 182 (CAS CATO-C4X-1140182)
- Lenvatinib Impurity 157 (CAS CATO-C4X-1140157)
- Lenvatinib Impurity 52 (CAS CATO-C4X-114052)
Recommended Standards
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- 1-(pentan-3-yl)-1H-pyrazole-3-carboxylic acid (CAS 1306603-93-9)
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