Azilsartan impurity 142 CAS CATO-C4X-1096142
| CAS No. | CATO-C4X-1096142 |
| Molecular Formula | C22H17N3O4 |
| Molecular Weight | 387.39 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Azilsartan impurity 142 is closely related to a flavonoid core, an amide group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Azilsartan impurity 142 (CAS CATO-C4X-1096142) is a certified pharmaceutical impurity reference standard with the molecular formula C22H17N3O4 and a molecular weight of 387.39 g/mol.
Azilsartan impurity 142 (C22H17N3O4) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Azilsartan impurity 142 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C22H17N3O4 |
| Molecular Weight | 387.39 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 3 |
Related Azilsartan Standards
- Azilsartan Impurity 17 (CAS CATO-C4X-109617)
- Azilsartan impurity 146 (CAS CATO-C4X-1096146)
- Azilsartan Impurity 10 (CAS 1863930-34-0)
- Azilsartan Impurity 132 (CAS CATO-C4X-1096132)
- Azilsartan Impurity 106 (CAS CATO-C4X-1096106)
- Azilsartan Impurity 74 (CAS 139481-33-7)
- Azilsartan Impurity 158 (CAS 183986-64-3)
- Azilsartan Impurity 16 (CAS 632322-61-3)
Recommended Standards
- Pomalidomide-5'-C5-acid (CAS 2205014-90-8)
- Pomalidomide 4'-alkylC5-acid (CAS 2225940-49-6)
- Candesartan Cilexetil Impurity 24 (CAS 139481-28-0)
- N6-(p-Methoxybenzyl)adenosine (CAS 23666-24-2)
- Benzbromarone Impurity 22 (CAS CATO-C4X-225022)
- Sitagliptin Impurity 90 HCl (CAS 1334244-24-4(free base))
- Argatroban Impurity 59 (CAS CATO-C4X-100759)
- (6-Aminoquinolin-5-yl)dimethylphosphine oxide (CAS 2498545-31-4)
- 2-Amino-3-(1h-benzo[d]imidazol-1-yl)-2-methylpropan-1-ol (CAS 1341133-87-6)
- 4-[(4-methyl-1h-pyrazol-1-yl)methyl]aniline (CAS 1183309-99-0)
- [1,1'-Biphenyl]-3,4'-dicarbaldehyde (CAS 869959-13-7)
- (E)-3-Butylidene-5-methylpyrrolidin-2-one (CAS 679818-45-2)
- Allopurinol impurity 12 (CAS CATO-C4X-145812)
- Erythropoietin Mimetic Peptide Sequence 20 (CAS 203397-62-0)
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