Olmesartan impurity 103 CAS CATO-C4X-1097103
| CAS No. | CATO-C4X-1097103 |
| Molecular Formula | C24H24N6O2 |
| Molecular Weight | 428.49 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Olmesartan impurity 103 is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
As a process- or degradation-related impurity, Olmesartan impurity 103 (CAS CATO-C4X-1097103, C24H24N6O2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Olmesartan impurity 103 (C24H24N6O2) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Olmesartan impurity 103 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C24H24N6O2 |
| Molecular Weight | 428.49 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 6 |
Related Olmesartan Standards
- Olmesartan Medoxomil EP Impurity B (CAS 849206-43-5)
- Olmesartan Impurity 21 (CAS 172875-98-8)
- Olmesartan Methyl Ketone (CAS 1227626-45-0)
- Olmesartan Medoxomilum EP Impurity A (CAS 144689-24-7)
- Olmesartan- D4 (CAS 1420880-41-6)
- Olmesartan-d6 Acid (CAS 1185144-74-4)
- Olmesartan Methyl Ether (CAS 1039762-40-7)
- Olmesartan Impurity 20 (CAS 1347262-29-6)
Recommended Standards
- Ibrutinib Impurity 4 (CAS 1288338-95-3)
- 2-Ethyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1-(triisopropylsilyl)-1H-pyrrolo[2,3-b]pyridine (CAS 1357387-65-5)
- 8-(4-([1,2,4]Triazolo[1,5-a]pyridin-6-yl)-3-(6-methylpyridin-2-yl)-1H-pyrazol-1-yl)-2-oxaspiro[4.5]decan-1-one (CAS 1097729-66-2)
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- 4-Chloro-2-methoxy-5-methylpyridine (CAS 1227578-49-5)
- 2-Benzyl-2-azabicyclo[2.2.1]Heptane-1-carbonitrile (CAS 1114824-09-7)
- 3-Fluoroquinoline-7-carboxylic acid (CAS 1841081-50-2)
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- 4-(4-Morpholin-4-yl-phenylcarbamoyl)-butyric acid (CAS 510764-91-7)
- Des-Pro36-Tirzepatide (CAS CATO-CPTD788937)
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