Ibrutinib Impurity 4 CAS 1288338-95-3
| CAS No. | 1288338-95-3 |
| Molecular Formula | C24H24N6O2 |
| Molecular Weight | 428.49 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a process- or degradation-related impurity, Ibrutinib Impurity 4 (CAS 1288338-95-3, C24H24N6O2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Ibrutinib Impurity 4 (C24H24N6O2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 16.0, corresponding to approximately 16 ring(s) or double-bond equivalent(s). With a molecular weight of 428.49 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO manufactures Ibrutinib Impurity 4 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C24H24N6O2 |
| Molecular Weight | 428.49 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Nitrogen Atoms | 6 |
Related Ibrutinib Standards
- Ibrutinib Impurity 123 (CAS CATO-C4X-1064123)
- Ibrutinib Impurity 77 (CAS CATO-C4X-106477)
- Ibrutinib Impurity 134 (CAS CATO-C4X-1064134)
- Ibrutinib Impurity 130 (CAS 1633352-71-2)
- Ibrutinib Impurity 196 (CAS CATO-C4X-1064196)
- Ibrutinib Racemate (CAS 936563-87-0)
- Ibrutinib (CAS 936563-96-1)
- Ibrutinib Impurity 1 (CAS 936563-97-2)
Recommended Standards
- 2-Ethyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1-(triisopropylsilyl)-1H-pyrrolo[2,3-b]pyridine (CAS 1357387-65-5)
- Olmesartan impurity 103 (CAS CATO-C4X-1097103)
- 8-(4-([1,2,4]Triazolo[1,5-a]pyridin-6-yl)-3-(6-methylpyridin-2-yl)-1H-pyrazol-1-yl)-2-oxaspiro[4.5]decan-1-one (CAS 1097729-66-2)
- Olmesartan Medoxomil EP Impurity B (CAS 849206-43-5)
- Ilaprazole Impurity 178 (CAS CATO-C4X-1130178)
- Bepotastine Impurity 5 (CAS CATO-C4X-18395)
- Riluzole Impurity 9 (CAS 1736-72-7)
- N-(9-Ethyl-9H-carbazol-3-yl)-3-oxobutanamide (CAS 331713-74-7)
- (6-Methylpyrazin-2-yl)methyl acetate (CAS 86725-83-9)
- (S)-2-Amino-N-(2-cyanobenzyl)-N-ethyl-3-methylbutanamide (CAS 1306109-05-6)
- 6-hydroxypyridazine-3-carboxylic acid (CAS 37972-69-3)
- 4-Iodo-1-naphthalenesulfonic acid (CAS 162109-21-9)
- 4-Bromoquinolin-8-amine (CAS 1416438-31-7)
- Fragment-[3-31]-Liraglutide (CAS CATO-C4X-199232)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com