Alogliptin impurity 87 CAS CATO-C4X-109987
| CAS No. | CATO-C4X-109987 |
| Molecular Formula | C14H21N2 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 297.24 g/mol gives Alogliptin impurity 87 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
As a process- or degradation-related impurity, Alogliptin impurity 87 (CAS CATO-C4X-109987, C14H21N2Br) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, bromine substitution, Alogliptin impurity 87 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 297.24 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C14H21N2 Br |
| Molecular Weight | 297.24 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 2 |
Related Alogliptin Standards
- Alogliptin Impurity 3 (CAS 1108731-49-2)
- Alogliptin Impurity 89 (CAS 1108732-05-3)
- Alogliptin impurity 77 HCl (CAS 1108732-05-3（free base）)
- Alogliptin Impurity 51 (CAS 1133421-35-8)
- Alogliptin Impurity 38 (CAS 120977-94-8)
- Alogliptin Impurity 16 (CAS 1217476-03-3)
- Alogliptin Impurity 33 (CAS 123-56-8)
- Alogliptin Impurity 69 (CAS 1243378-31-5)
Recommended Standards
- Clonazepam impurity 12 (CAS 2246723-47-5)
- N-Nitroso Ivabradine impurity 85 (CAS CATO-C4X-111985)
- Posaconazole Impurity 69 (CAS CATO-C4X-120869)
- (9H-purin-6-yl)-L-tryptophan (CAS 1173674-58-2)
- N'-Desmethyl Amonafide-d5 (CAS 1215400-25-1)
- 2-(4-(2-Bromoethyl)phenoxy)tetrahydro-2H-pyran (CAS 1198772-94-9)
- 5-(4-Bromophenyl)-2,3'-bipyridine (CAS 917897-54-2)
- 6-Chloro-4-(piperidin-4-ylthio)quinoline dihydrochloride (CAS 882865-05-6)
- 3-(4-Chlorophenyl)-N,N-dimethyl-4-oxo-3,4-dihydrophthalazine-1-carboxamide (CAS 339021-29-3)
- Epidermal Growth Factor Receptor Peptide (985-996) (CAS 96249-43-3)
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