Linagliptin Impurity 124 CAS CATO-C4X-1101124
| CAS No. | CATO-C4X-1101124 |
| Molecular Formula | C25H26N8O4 |
| Molecular Weight | 502.53 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 502.53 g/mol gives Linagliptin Impurity 124 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
As a process- or degradation-related impurity, Linagliptin Impurity 124 (CAS CATO-C4X-1101124, C25H26N8O4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Linagliptin Impurity 124 (C25H26N8O4) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Linagliptin Impurity 124 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C25H26N8O4 |
| Molecular Weight | 502.53 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 17.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 8 |
Related Linagliptin Standards
- Linagliptin impurity 139 (CAS 2137744-33-1)
- Linagliptin Impurity 40 (CAS CATO-C4X-110140)
- Linagliptin impurity 155 (CAS CATO-C4X-1101155)
- Linagliptin Impurity 57 (CAS 2416949-69-2)
- Linagliptin Impurity 33 (CAS CATO-C4X-110133)
- Linagliptin impurity 163 (CAS CATO-C4X-1101163)
- Linagliptin Impurity 111 (CAS CATO-C4X-1101111)
- Linagliptin Impurity 38 (CAS 1803079-49-3)
Recommended Standards
- 1H-Indole-1-carboxylic acid, 2-borono-5-[[4-[[[(1,1-dimethylethyl)dimethylsilyl]oxy]methyl]-1-piperidinyl]methyl]-, 1-(1,1-dimethylethyl) ester (CAS 913388-71-3)
- Lasmiditan Impurity 48 (CAS CATO-C4X-247848)
- rac 2,4-Dimethoxy-6-[[(trifluoromethyl)sulfonyl]oxy]benzoic Acid 1-Methyl-5-oxo-9-decen-1-yl Ester-d6 (CAS 1246815-12-2)
- 4-(3-Fluoro-5-morpholinophenyl)-N-(4-(3-morpholino-1H-1,2,4-triazol-1-yl)phenyl)pyrimidin-2-amine (CAS 1128096-64-9)
- Metoprolol Impurity 2 (Mixture of Z and E Isomers) (CAS 82961-02-2)
- Imatinib Mesilate EP Impurity H (CAS 350-03-8)
- chondroitin sulfate impurity G (CAS CATO-C4X-32817)
- trans-2-(2-Ethylphenyl)cyclohexanol (CAS 933674-53-4)
- 4-(Neopentyloxy)pyridin-3-amine (CAS 1447961-62-7)
- 5-Bromo-2-(2-chloro-5-methylphenoxy)aniline (CAS 946664-95-5)
- 1-(o-Tolyl)-1,4-diazepane acetate (CAS 1185429-26-8)
- Ganciclovir Impurity 29 (CAS CATO-C4X-102129)
- methyl 4-fluoro-3-iodo-1H-indazole-6-carboxylate (CAS 885521-35-7)
- Semaglutide impurity 107 (CAS CATO-C4X-2226107)
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