Lasmiditan Impurity 48 CAS CATO-C4X-247848
| CAS No. | CATO-C4X-247848 |
| Molecular Formula | C26H29F3N4O3 |
| Molecular Weight | 502.53 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Lasmiditan Impurity 48 is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Lasmiditan Impurity 48 (CAS CATO-C4X-247848) is a certified pharmaceutical impurity reference standard with the molecular formula C26H29F3N4O3 and a molecular weight of 502.53 g/mol.
Based on its molecular formula C26H29F3N4O3, Lasmiditan Impurity 48 contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 502.53 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C26H29F3N4O3 |
| Molecular Weight | 502.53 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
Related Lasmiditan Standards
- Lasmiditan Impurity 57 (CAS CATO-C4X-247857)
- Lasmiditan Impurity 51 (CAS CATO-C4X-247851)
- Lasmiditan Impurity 7 (CAS CATO-C4X-24787)
- Lasmiditan Impurity 45 (CAS CATO-C4X-247845)
- Lasmiditan Impurity 65 (CAS CATO-C4X-247865)
- Lasmiditan Impurity 70 (CAS CATO-C4X-247870)
- Lasmiditan Impurity 14 (CAS CATO-C4X-247814)
- Lasmiditan Impurity 11 (CAS CATO-C4X-247811)
Recommended Standards
- Linagliptin Impurity 124 (CAS CATO-C4X-1101124)
- 4-(3-Fluoro-5-morpholinophenyl)-N-(4-(3-morpholino-1H-1,2,4-triazol-1-yl)phenyl)pyrimidin-2-amine (CAS 1128096-64-9)
- 1H-Indole-1-carboxylic acid, 2-borono-5-[[4-[[[(1,1-dimethylethyl)dimethylsilyl]oxy]methyl]-1-piperidinyl]methyl]-, 1-(1,1-dimethylethyl) ester (CAS 913388-71-3)
- (1R,2R)-2-Hydroxy-1,2-diphenylethyl 2-(diphenylphosphino)benzoate (CAS 1220999-75-6)
- Fosaprepitant Impurity 42 (CAS CATO-C4X-116842)
- Tolvaptan Impurity 89 (CAS 137977-65-2)
- Fludarabine Phosphate EP Impurity C (CAS 548774-53-4)
- Ethyl 3-Oxo-3-[4-(trifluoromethoxy)phenyl]propionate (CAS 252955-06-9)
- Daptomycin Impurity B (CAS CATO-C4X-137857)
- Potassium dicyanoargentate (CAS 506-61-6)
- 1-Cyclopropoxy-2-methoxy-3-nitrobenzene (CAS 1243415-15-7)
- 1-Amino-2-methyl-1H-benzo[d]imidazol-6-ol (CAS 158591-13-0)
- 2-((5-(4-(tert-Butyl)phenyl)-4-(4-methoxyphenyl)-4H-1,2,4-triazol-3-yl)thio)-N-(2,4-dimethylphenyl)acetamide (CAS 477313-65-8)
- (D-Trp32)-Neuropeptide Y (porcine) trifluoroacetate salt (CAS 153549-78-1)
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