Gefitinib impurity 71 CAS CATO-C4X-111771
| CAS No. | CATO-C4X-111771 |
| Molecular Formula | C14H16N2O4 |
| Molecular Weight | 276.29 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Gefitinib impurity 71 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
CATO supplies Gefitinib impurity 71 (CAS CATO-C4X-111771), a pharmacopoeial impurity reference standard (molecular formula C14H16N2O4, MW 276.29 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C14H16N2O4, Gefitinib impurity 71 contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 276.29 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C14H16N2O4 |
| Molecular Weight | 276.29 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 2 |
Related Gefitinib Standards
- Gefitinib Impurity 55 (CAS 675126-28-0)
- Gefitinib Impurity 57 (CAS 861453-11-4)
- Gefitinib Impurity 77 (CAS CATO-C4X-111777)
- Gefitinib Impurity 48 (CAS 385784-72-5)
- Gefitinib Impurity 56 (CAS 675126-27-9)
- Gefitinib Impurity 30 (CAS CATO-C4X-111730)
- Gefitinib Impurity 9 (CAS CATO-C4X-11179)
- Gefitinib Impurity 97 (CAS CATO-C4X-111797)
Recommended Standards
- Dabigatran Impurity 82 (CAS 1900865-84-0)
- Avibactam Impurity 22 (CAS 1174020-25-7)
- Ibrutinib Impurity 145 (CAS 1881246-01-0)
- Avibactam Impurity 52 (CAS 2064219-14-1)
- Opicapone impurity 63 (CAS CATO-C4X-240463)
- Naloxone Impurity 17 (CAS CATO-C4X-149317)
- Donepezil Open-Ring Hydroxy Acid (Na Salt) (CAS CATO-C4X-103971)
- N,N-Dimethyl-2-(p-tolyloxy)ethanamine (CAS 51344-14-0)
- (2-(Benzyloxy)-2-oxoethyl)triphenylphosphonium bromide (CAS 78385-36-1)
- Ethyl 2,5-dichlorobenzoylformate (CAS 951888-22-5)
- Ethyl 8-(4-methylbenzoyl)-5-oxo-1,2,3,5-tetrahydroimidazo[1,2-a]pyridine-7-carboxylate (CAS 1263212-69-6)
- 2-Methoxyacridin-9(10H)-one (CAS 49742-72-5)
- 1-(4-Fluoro-2-methoxyphenyl)cyclopropanamine (CAS 1314661-92-1)
- Semaglutide impurity 199 (CAS CATO-C4X-2226199)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com