Gefitinib impurity 69 CAS CATO-C4X-111769
| CAS No. | CATO-C4X-111769 |
| Molecular Formula | C15H19N3O5 |
| Molecular Weight | 321.33 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Gefitinib impurity 69.
As a process- or degradation-related impurity, Gefitinib impurity 69 (CAS CATO-C4X-111769, C15H19N3O5) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Gefitinib impurity 69 (C15H19N3O5) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Gefitinib impurity 69 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C15H19N3O5 |
| Molecular Weight | 321.33 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 3 |
Related Gefitinib Standards
- Gefitinib Impurity 48 (CAS 1006378-06-8)
- Gefitinib Impurity 54 (CAS 675126-26-8)
- Gefitinib impurity 68 (CAS CATO-C4X-111768)
- Gefitinib Impurity 89 (CAS CATO-C4X-111789)
- Gefitinib Impurity 7 (CAS 184475-71-6)
- Gefitinib impurity 64 (CAS CATO-C4X-111764)
- Gefitinib EP Impurity A (CAS 199327-61-2)
- Gefitinib Impurity 41 (CAS CATO-C4X-111741)
Recommended Standards
- Norepinephrine Impurity 122 (CAS CATO-C4X-1514122)
- Famciclovir (CAS 104227-87-4)
- Famciclovir Impurity 3 (CAS CATO-C4X-16423)
- Amlodipine Impurity 48 (CAS CATO-C4X-109548)
- Avanafil Impurity 34 (CAS 759408-08-7)
- Nisoldipine Impurity 6 (CAS 61312-59-2)
- Macitentan impurity 53 (CAS 2211054-46-3)
- 4-(1,3-Dioxolan-2-yl)-3-fluorobenzophenone (CAS 898760-12-8)
- 4-(4-Methoxybenzyl)-2-methyl-6-phenylpyridazin-3(2H)-one (CAS 64657-96-1)
- Ethyl 2-amino-2-(o-tolyl)acetate (CAS 366018-88-4)
- 4-(Difluoromethyl)-2-iodo-5-methoxypyridine-3-sulfonamide (CAS 1805533-89-4)
- 1-(5,6-Dimethylpyrimidin-4-yl)pyrrolidine-3-carboxylic acid (CAS 1708268-54-5)
- 3-Ethoxy-5-methyl-4-(pyridin-2-yl)isoxazole (CAS 342424-90-2)
- Peptide 434 (CAS CATO-CPTD788434)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com