Avanafil Impurity 76 CAS CATO-C4X-111876
| CAS No. | CATO-C4X-111876 |
| Molecular Formula | C41H41Cl2N13O5 |
| Molecular Weight | 866.75 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Avanafil Impurity 76 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies Avanafil Impurity 76 (CAS CATO-C4X-111876), a pharmacopoeial impurity reference standard (molecular formula C41H41Cl2N13O5, MW 866.75 g/mol) used for the identification and quantification of trace impurities in APIs.
Avanafil Impurity 76 (C41H41Cl2N13O5) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C41H41Cl2N13O5 |
| Molecular Weight | 866.75 g/mol |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 27.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 13 |
Related Avanafil Standards
- Avanafil Impurity 132 (CAS CATO-C4X-1118132)
- Avanafil Impurity 42 (CAS CATO-C4X-1118142)
- Avanafil Impurity 12 (CAS CATO-C4X-111812)
- Avanafil Impurity 32 (CAS CATO-C4X-111832)
- Avanafil Impurity 38 (CAS CATO-C4X-111838)
- Avanafil Impurity 57 (CAS CATO-C4X-111857)
- Avanafil Impurity 137 (CAS CATO-C4X-1118137)
- Avanafil Impurity 41 (CAS CATO-C4X-1118141)
Recommended Standards
- (3aS,5R,6R,7S,7aS)-5-(acetoxymethyl)-2-(((3aS,5R,6R,7S,7aS)-5-((((3aS,5R,6R,7S,7aS)-6,7-diacetoxy-5-(acetoxymethyl)-2-methyltetrahydro-5H-[1,3]dioxolo[4,5-b]pyran-2-yl)oxy)methyl)-6-hydroxy-2-methyltetrahydro-5H-[1,3]dioxolo[4,5-b]pyran-7-yl)oxy)-2-methyltetrahydro-5H-[1,3]dioxolo[4,5-b]pyran-6,7-diyl diacetate (CAS 230963-26-5)
- 92396-91-3 54,54-Dichloro-13,26,39,52,53,55,56,57-octaaza-54-silatetradecacyclo[25.25.3.1~14,25~.1~40,51~.0~2,11~.0~4,9~.0~12,53~.0~15,24~.0~17,22~.0~28,37~.0~30,35~.0~38,55~.0~41,50~.0~43,48~]heptapentacontane (non-preferred name) DTXSID10746568 (CAS 92396-91-3)
- Procyanidin C1 (CAS 37064-30-5)
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- Fingolimod EP Impurity B (Fingolimod Heptyl Impurity) (CAS 745767-97-9)
- Irbesartan Impurity 35 (CAS 2758005-15-9)
- Mianserin Impurity 86 (CAS CATO-C4X-136986)
- (2S,3S)-3-Amino-2-hydroxy-3-(p-tolyl)propanoic acid (CAS 1217709-00-6)
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- 3-(6-(3-Chlorophenyl)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl)propanoic acid (CAS 1255782-22-9)
- 2-(3-Bromophenyl)-4,5-dihydro-1,3-oxazole (CAS 792913-45-2)
- n-Methyl-n'-(naphthalen-2-yl)benzenecarboximidamide (CAS 878259-93-9)
- 3-Ethoxybenzofuran (CAS 138173-85-0)
- Peptide Impurity 09 X TFA Salt (CAS CATO-CPTD788809)
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