Avanafil Impurity 57 CAS CATO-C4X-111857
| CAS No. | CATO-C4X-111857 |
| Molecular Formula | C41H45Cl2N11O6 |
| Molecular Weight | 858.77 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 858.77 g/mol gives Avanafil Impurity 57 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
As a process- or degradation-related impurity, Avanafil Impurity 57 (CAS CATO-C4X-111857, C41H45Cl2N11O6) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Avanafil Impurity 57 (C41H45Cl2N11O6) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Avanafil Impurity 57 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C41H45Cl2N11O6 |
| Molecular Weight | 858.77 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 24.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 11 |
Related Avanafil Standards
- Avanafil Impurity 12 (CAS CATO-C4X-111812)
- Avanafil Impurity 32 (CAS CATO-C4X-111832)
- Avanafil Impurity 38 (CAS CATO-C4X-111838)
- Avanafil Impurity 42 (CAS CATO-C4X-1118142)
- Avanafil Impurity 132 (CAS CATO-C4X-1118132)
- Avanafil Impurity 76 (CAS CATO-C4X-111876)
- Avanafil Impurity 137 (CAS CATO-C4X-1118137)
- Avanafil Impurity 41 (CAS CATO-C4X-1118141)
Recommended Standards
- N-Mal-N-bis(PEG4-NHS ester) (CAS 2112738-60-8)
- Thymic Factor (CAS 63958-90-7)
- Ceftaroline Fosamil Impurity 1 (CAS 1277090-03-5)
- Ir(p-CF3-ppy)3 (CAS 500295-52-3)
- Rosuvastatin Impurity 55 (CAS 289042-10-0)
- Sitagliptin Impurity 68 (CAS CATO-C4X-114468)
- Vitamin K1 Impurity 48 (CAS CATO-C4X-220748)
- Methyl 4-amino-4-(4-fluoro-3-methylphenyl)butanoate (CAS 1506423-83-1)
- 4-(2,2,2-Trifluoroethyl)-1H-pyrazol-3-amine (CAS 1057259-62-7)
- 5,6-Dihydro-1H-imidazo[1,5,4-de]quinoxalin-2(4H)-one (CAS 163120-50-1)
- Methyl thieno[2,3-c]pyridine-3-carboxylate (CAS 28783-21-3)
- 4-(5,6,7,8-Tetrahydro-1,8-naphthyridin-2-yl)butanoic acid (CAS 332884-21-6)
- Shancigusin I (CAS 1435488-35-9)
- PACAP-Related Peptide (PRP), rat (CAS 132769-35-8)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com