Palbociclib Impurity 182 CAS CATO-C4X-1125182
| CAS No. | CATO-C4X-1125182 |
| Molecular Formula | C12H15N3O2 |
| Molecular Weight | 233.27 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Palbociclib Impurity 182 (CAS CATO-C4X-1125182) is a certified pharmaceutical impurity reference standard with the molecular formula C12H15N3O2 and a molecular weight of 233.27 g/mol.
Based on its molecular formula C12H15N3O2, Palbociclib Impurity 182 contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 233.27 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H15N3O2 |
| Molecular Weight | 233.27 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 3 |
Related Palbociclib Standards
- Palbociclib Impurity 184 (CAS CATO-C4X-1125184)
- Palbociclib Impurity 169 (CAS CATO-C4X-1125169)
- Palbociclib Impurity 126 (CAS 2089333-12-8)
- Palbociclib Impurity 46 (CAS 1244949-62-9)
- Palbociclib Impurity 197 (CAS 1314997-73-3)
- Palbociclib Impurity 209 (CAS CATO-C4X-1125209)
- Palbociclib Impurity 151 (CAS CATO-C4X-1125151)
- Palbociclib Impurity 173 (CAS CATO-C4X-1125173)
Recommended Standards
- Gefitinib Impurity 25 (CAS 385784-68-9)
- 347840-95-3 4-(3,4-Dimethoxy-phenyl)-5-methyl-2H-pyrazol-3-ylamine 4-(3,4-dimethoxy-phenyl)-5-methyl-2 h-pyrazol-3-ylamine 4-(3,4-dimethoxyphenyl)-3-methyl-1h-pyrazol-5-amine (CAS 347840-95-3)
- Bendamustine Impurity 29 (CAS 914626-62-3)
- tert-Butyl 6-amino-1H-pyrrolo[2,3-b]pyridine-1-carboxylate (CAS 1998152-01-4)
- ZHC-116 Impurity 5 (CAS CATO-C4X-23885)
- Meglumine Impurity 12 (CAS CATO-C4X-214212)
- Famotidine Impurity 39 (CAS CATO-C4X-139239)
- 2-Amino-3,4-dihydro-7-methoxy-2H-1-naphthalenone HCl (CAS 2472-16-4)
- (-)-Phaseic Acid (CAS 24394-14-7)
- 1-{1H-pyrrolo[2,3-b]pyridin-4-yl}ethan-1-one (CAS 915415-16-6)
- 3,4,5-Trifluoronitrobenzene (CAS 66684-58-0)
- 2-(4-(Dimethylamino)benzylidene)-5-oxopyrazolidin-2-ium-1-ide (CAS 19948-39-1)
- 1-(2-Bromo-1-(cyclopentyloxy)ethyl)-2-fluorobenzene (CAS 1247504-14-8)
- Semaglutide Impurity 146 (CAS 2645421-68-5)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com