Sildenafil Impurity 284 CAS CATO-C4X-1128284

Purity 97%+In StockPharmacopoeial Impurity Standards
CAS No.CATO-C4X-1128284
Molecular FormulaC21H28N4O5S
Molecular Weight448.54 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Sildenafil Impurity 284 CAS CATO-C4X-1128284 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 448.54 g/mol gives Sildenafil Impurity 284 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

CATO supplies Sildenafil Impurity 284 (CAS CATO-C4X-1128284), a pharmacopoeial impurity reference standard (molecular formula C21H28N4O5S, MW 448.54 g/mol) used for the identification and quantification of trace impurities in APIs.

Based on its molecular formula C21H28N4O5S, Sildenafil Impurity 284 contains a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 448.54 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC21H28N4O5S
Molecular Weight448.54 g/mol
Purity97%+
StorageStore in a cool place (≤25°C), protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)10.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
Nitrogen Atoms4
Sulfur Atoms1

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