Sildenafil Impurity 87 CAS CATO-C4X-112887
| CAS No. | CATO-C4X-112887 |
| Molecular Formula | C26H40N6O5S |
| Molecular Weight | 548.70 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Sildenafil Impurity 87 is closely related to a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Sildenafil Impurity 87 (CAS CATO-C4X-112887) is a certified pharmaceutical impurity reference standard with the molecular formula C26H40N6O5S and a molecular weight of 548.70 g/mol.
Sildenafil Impurity 87 (C26H40N6O5S) contains a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Sildenafil Impurity 87 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C26H40N6O5S |
| Molecular Weight | 548.70 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 6 |
| Sulfur Atoms | 1 |
Related Sildenafil Standards
- Sildenafil Impurity 78 (CAS CATO-C4X-112878)
- Sildenafil Impurity 309 (CAS CATO-C4X-1128309)
- Sildenafil Impurity 258 (CAS 1007310-62-4)
- Sildenafil Impurity 33 (CAS CATO-C4X-112833)
- Sildenafil Impurity 297 (CAS CATO-C4X-1128297)
- Sildenafil Impurity 277 (CAS CATO-C4X-1128277)
- Sildenafil Impurity 262 (CAS CATO-C4X-1128262)
- Sildenafil Impurity 75 (CAS 2253964-66-6)
Recommended Standards
- 2,2',4,5,5'-Pentabromobiphenyl (CAS 67888-96-4)
- Bis(pentafluorophenyl)(1,5-cyclo-octadiene)palladium(II) (CAS 105286-78-0)
- PBB No. 103 (CAS 59080-39-6)
- Octacosahydrodibenzo[b,q][1,4,7,10,13,16,19,22,25,28]decaoxacyclotriacontine (CAS 17455-26-4)
- Lercanidipine Impurity 29 (CAS CATO-C4X-136429)
- Telmisartan Impurity 88 (CAS CATO-C4X-135988)
- Thioctic acid Impurity 36 (CAS 2635383-46-7)
- Morpholine-4-sulfonic acid (CAS 6427-18-5)
- N1-[2,6-Bis(1-methylethyl)phenyl]-N2-[[2-(dicyclohexylphosphino)phenyl]methyl]-1,2-ethanediamine (CAS 1450877-17-4)
- 1-(4-Amino-2-chlorophenyl)pentan-1-one (CAS 1339841-76-7)
- 2-(Tert-butyl)-4-(4-chlorophenyl)-5-methyl-1,2-dihydro-3H-pyrazol-3-one (CAS 400076-62-2)
- 2-(Difluoromethyl)-3-hydroxy-6-(trifluoromethoxy)pyridine-4-carboxaldehyde (CAS 1804347-89-4)
- Ethyl 2-(5-Amino-2-pyrimidyl)acetate (CAS 944902-41-4)
- Des-Pro36-37-Tirzepatide (CAS CATO-CPTD788938)
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