Ilaprazole impurity 198 CAS CATO-C4X-1130198
| CAS No. | CATO-C4X-1130198 |
| Molecular Formula | C8H9Cl2NO |
| Molecular Weight | 206.07 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 206.07 g/mol gives Ilaprazole impurity 198 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
As a process- or degradation-related impurity, Ilaprazole impurity 198 (CAS CATO-C4X-1130198, C8H9Cl2NO) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Ilaprazole impurity 198 (C8H9Cl2NO) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H9Cl2NO |
| Molecular Weight | 206.07 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Ilaprazole Standards
- Ilaprazole Impurity N1 (CAS 84445-90-9)
- Ilaprazole Impurity 30 (CAS CATO-C4X-113030)
- Ilaprazole Impurity 101 (CAS 473537-16-5)
- Ilaprazole Impurity 148 (CAS CATO-C4X-1130148)
- Ilaprazole impurity 192 (CAS CATO-C4X-1130192)
- Ilaprazole Impurity 36 (CAS 1018229-53-2)
- Ilaprazole Impurity 133 (CAS 67382-07-4)
- Ilaprazole Impurity 145 (CAS 67382-06-3)
Recommended Standards
- Avanafil Impurity 25 (CAS 36167-94-9)
- Econazole Impurity 13 (CAS 88965-93-9)
- Avanafil Impurity 133 (CAS 1508194-63-5)
- 2,6-Dichloro-4-methoxybenzenemethanamine (CAS 160522-40-7)
- Alverine Citrate EP Impurity D (CAS 2732347-30-5(free base))
- CAS CATO-C4X-34244 (CAS CATO-C4X-34244)
- Carboplatin Impurity 6 (CAS 3721-95-7)
- Temanogrel (CAS 887936-68-7)
- Disperse Blue 102 (CAS 12222-97-8)
- 5-Bromocinnolin-4(1H)-one (CAS 1076-15-9)
- 1,5-Dihydrobenzo[1,2-d:4,5-d’]bis([1,2,3]triazole) (CAS 7221-63-8)
- Methyl 2,5-dichloro-6-cyanonicotinate (CAS 1341232-15-2)
- 3-((4,6-Dimethylpyrimidin-2-yl)amino)-4-methyl-4H-benzo[e][1,2,4]thiadiazine 1,1-dioxide hydrochloride (CAS 317821-65-1)
- Atrial Natriuretic Polypeptide (4-28), human (CAS 95896-08-5)
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