Avanafil Impurity 25 CAS 36167-94-9
| CAS No. | 36167-94-9 |
| Molecular Formula | C8H9Cl2NO |
| Molecular Weight | 206.07 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Avanafil Impurity 25 is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies Avanafil Impurity 25 (CAS 36167-94-9), a pharmacopoeial impurity reference standard (molecular formula C8H9Cl2NO, MW 206.07 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C8H9Cl2NO, Avanafil Impurity 25 contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 206.07 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Avanafil Impurity 25 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H9Cl2NO |
| Molecular Weight | 206.07 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1967 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Avanafil Standards
- Avanafil Impurity 110 (CAS 1368440-33-8)
- Avanafil Impurity 133 (CAS 1508194-63-5)
- Avanafil Impurity 160 (CAS 1202002-16-1)
- Avanafil Impurity 55 (CAS 5909-24-0)
- Avanafil Impurity 70 (CAS 32897-26-0)
- Avanafil Impurity 108 (CAS CATO-C4X-1118108)
- Avanafil Impurity 111 (CAS CATO-C4X-1118111)
- Avanafil Impurity 33 (CAS 247569-72-8)
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