Brexpiprazole Impurity 143 CAS CATO-C4X-1131143
| CAS No. | CATO-C4X-1131143 |
| Molecular Formula | C29H35N3O3S |
| Molecular Weight | 505.67 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
As a process- or degradation-related impurity, Brexpiprazole Impurity 143 (CAS CATO-C4X-1131143, C29H35N3O3S) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Brexpiprazole Impurity 143 (C29H35N3O3S) contains a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C29H35N3O3S |
| Molecular Weight | 505.67 g/mol |
| Purity | ≥95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Brexpiprazole Standards
- Brexpiprazole Impurity 50 (CAS CATO-C4X-113150)
- Brexpiprazole Impurity 79 (CAS CATO-C4X-113179)
- Brexpiprazole impurity 115 (CAS CATO-C4X-1131115)
- Brexpiprazole Impurity 11 (CAS 2250242-22-7)
- Brexpiprazole Impurity 59 (CAS CATO-C4X-113159)
- Brexpiprazole Impurity 61 (CAS CATO-C4X-113161)
- Brexpiprazole impurity 122 (CAS CATO-C4X-1131122)
- Brexpiprazole impurity 123 (CAS CATO-C4X-1131123)
Recommended Standards
- C8 Ceramide-1-phosphate (CAS 887353-95-9)
- Pioglitazone impurity 29 (CAS CATO-C4X-138329)
- Raloxifene-d4 Bismethyl Ether (CAS 1185006-58-9)
- N-(3-Cyano-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)-2-{[3-cyano-6-methyl-4-(thiophen-3-yl)-5,6,7,8-tetrahydro-1,6-naphthyridin-2-yl]sulfanyl}acetamide (CAS 445383-39-1)
- Clomipramine EP Impurity B (CAS 50-49-7)
- Ketorolac Impurity 57 (CAS CATO-C4X-166957)
- Carbazochrome Impurity 35 (CAS CATO-C4X-229135)
- 1-(2-Aminoethyl)-1,3-dihydrobenzo[c][1,2,5]thiadiazole 2,2-dioxide (CAS 1016784-35-2)
- 5-Chloro-2-(3-fluorophenyl)isothiazol-3(2H)-one (CAS 1213258-30-0)
- m-PEG7-azide (CAS 208987-04-6)
- 2-tert-Butyl-1-methyl-1h-1,3-benzodiazol-5-amine (CAS 1250823-86-9)
- N-(3-(2,2-difluoroethoxy)benzyl)cyclopropanamine (CAS 1179136-66-3)
- 2-((3,4-Dihydroquinoxalin-1(2H)-yl)methylene)malononitrile (CAS 6687-88-3)
- Peptide Impurity 28 (CAS 1350456-64-2)
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