Olaparib Impurity 94 CAS CATO-C4X-113594
| CAS No. | CATO-C4X-113594 |
| Molecular Formula | C16H9ClFN3 |
| Molecular Weight | 297.71 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Olaparib Impurity 94 is closely related to a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Olaparib Impurity 94 (CAS CATO-C4X-113594) is a certified pharmaceutical impurity reference standard with the molecular formula C16H9ClFN3 and a molecular weight of 297.71 g/mol.
The molecular framework of Olaparib Impurity 94 (C16H9ClFN3) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Olaparib Impurity 94 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C16H9ClFN3 |
| Molecular Weight | 297.71 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
Related Olaparib Standards
- Olaparib Impurity 2 (CAS 1956340-97-8)
- Olaparib Impurity 47 (CAS CATO-C4X-113547)
- Olaparib Impurity 56 (CAS CATO-C4X-113556)
- Olaparib Impurity 97 (CAS CATO-C4X-113597)
- Olaparib Impurity 1 (CAS 763114-26-7)
- Olaparib Impurity 159 (CAS CATO-C4X-1135159)
- Olaparib Impurity 38 (CAS CATO-C4X-113538)
- Olaparib Impurity 148 (CAS CATO-C4X-1135148)
Recommended Standards
- Ethyl 3-(2-chloro-6-fluorophenyl)-2-(isoxazol-5-yl)propanoate (CAS 477888-06-5)
- Pefloxacin Mesilate Dihydrate EP Impurity G (CAS 70458-94-5)
- 4'-Nitro-[1,1'-biphenyl]-4-sulfonyl chloride (CAS 20443-75-8)
- Pefloxacin Impurity 2 (CAS CATO-C4X-23332)
- Sitafloxacin Impurity 26 HCl (CAS 148693-51-0(Free Acid))
- Orlistat impurity 45 (CAS CATO-C4X-149945)
- Rosuvastatin Impurity 31 (CAS 2095786-11-9)
- tert-Butyl 2-amino-7-methyl-6,7-dihydrothiazolo[5,4-c]pyridine-5(4H)-carboxylate (CAS 1253415-55-2)
- 3,9-diazatricyclo[8.4.0.0^{3,7}]tetradeca-1(10),11,13-triene (CAS 24919-43-5)
- Calcium selenide (CAS 1305-84-6)
- 4-Phenylazo-1-naphthylamine (CAS 131-22-6)
- Polycarbonate (3 Strips, 2'' x 2 1/2'' each) (CAS 25766-59-0)
- Loxoprofen impurity 100 (CAS CATO-C4X-1488100)
- Insulin Glargine Metabolite M2 (CAS CATO-CPTD788867)
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