Dapagliflozin Impurity 40 CAS CATO-C4X-113840
| CAS No. | CATO-C4X-113840 |
| Molecular Formula | C19H21ClO6 |
| Molecular Weight | 380.82 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Dapagliflozin Impurity 40 (CAS CATO-C4X-113840) is a certified pharmaceutical impurity reference standard with the molecular formula C19H21ClO6 and a molecular weight of 380.82 g/mol.
The molecular framework of Dapagliflozin Impurity 40 (C19H21ClO6) is characterized by a flavonoid core, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C19H21ClO6 |
| Molecular Weight | 380.82 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
Related Dapagliflozin Standards
- Dapagliflozin Impurity 13 (CAS 864070-37-1)
- Dapagliflozin Impurity 23 (CAS 1103738-26-6)
- Dapagliflozin Impurity N31 (CAS 2305949-33-9)
- Dapagliflozin Impurity 175 (CAS CATO-C4X-1138175)
- Dapagliflozin Impurity 129 (CAS CATO-C4X-1138129)
- Dapagliflozin Impurity 32 (CAS 2452300-89-7)
- Dapagliflozin Impurity 74 (CAS 1298086-29-9)
- Dapagliflozin Impurity 127 (CAS CATO-C4X-1138127)
Recommended Standards
- N-(6-Amino-2,4-dioxo-1,3-dipropyl-1,2,3,4-tetrahydropyrimidin-5-yl)-3-chloro-4-hydroxybenzamide (CAS 102587-97-3)
- Amlodipine Impurity 19 (CAS CATO-C4X-109519)
- N-(6-amino-1-benzyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)-2-chloro-N-(3-methoxypropyl)acetamide (CAS 730950-29-5)
- Amlodipine Impurity 18 (CAS 1809326-44-0)
- Eltrombopag Impurity 57 (CAS 893736-72-6)
- Ensifentrine impurity 40 (CAS CATO-C4X-335340)
- Palonosetron Impurity 15 (CAS 135729-78-1)
- (R)-2-([1,1'-Biphenyl]-4-yl)-2-aminoacetic acid (CAS 1228559-61-2)
- N-(2-(dimethylamino)phenyl)acetamide (CAS 25116-01-2)
- 1-Amino-2-(tetrahydro-2h-pyran-4-yl)propan-2-ol (CAS 1539622-05-3)
- N-(2,4-Dimethyl-6-oxo-1,6-dihydropyrimidin-5-yl)-4-methylbenzamide (CAS 773834-81-4)
- 4-Chloro-5-(methoxycarbonyl)thiophene-2-boronic acid (CAS 2096331-56-3)
- 3-Chlorooxetane (CAS 4741-80-4)
- a2,3-Sialylglycopeptide (CAS 189035-43-6)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com