Eltrombopag Impurity 57 CAS 893736-72-6
| CAS No. | 893736-72-6 |
| Molecular Formula | C13H10O3 |
| Molecular Weight | 214.22 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Eltrombopag Impurity 57.
Eltrombopag Impurity 57 (CAS 893736-72-6) is a certified pharmaceutical impurity reference standard with the molecular formula C13H10O3 and a molecular weight of 214.22 g/mol.
Based on its molecular formula C13H10O3, Eltrombopag Impurity 57 contains a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 214.22 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Eltrombopag Impurity 57 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C13H10O3 |
| Molecular Weight | 214.22 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
Related Eltrombopag Standards
- Eltrombopag Impurity 43 (CAS 223127-00-2)
- Eltrombopag Impurity 31 (CAS 4291-30-9)
- Eltrombopag Impurity 30 (CAS CATO-C4X-119830)
- Eltrombopag Impurity 34 (CAS 13073-25-1)
- Eltrombopag Impurity 37 (CAS 7693-52-9)
- Eltrombopag Impurity 102 (CAS 118048-94-5)
- Eltrombopag Impurity 119 (CAS CATO-C4X-1198119)
- Eltrombopag Impurity 123 (CAS CATO-C4X-1198123)
Recommended Standards
- Pioglitazone impurity 56 (CAS 1258625-43-2)
- Terbutaline impurity 69 (CAS 39642-87-0)
- Nicotinamide Impurity 11 (CAS 39642-60-9)
- 3-((4-Hydroxyphenyl)amino)-4-iminocyclohexa-2,5-dien-1-one (CAS 1332075-11-2)
- Doxofylline Impurity 14 (CAS 7029-96-1)
- Tetrabenazine Impurity 42 (CAS CATO-C4X-274842)
- Ferulic Acid Impurity 7 (CAS CATO-C4X-22727)
- 2-Hydroxymethyl-2,3-dihydrobenzofuran (CAS 66158-96-1)
- tert-Butyl ((3-(3,4-difluorophenyl)-4,5-dihydroisoxazol-5-yl)methyl)carbamate (CAS 1488407-59-5)
- o-3M3FBS (CAS 313981-55-4)
- 3-(2-(aminomethyl)-1H-imidazol-5-yl)benzonitrile dihydrochloride (CAS 1421601-94-6)
- Ethyl 4-hydroxy-2,6,7-trimethylquinoline-3-carboxylate (CAS 88960-39-8)
- 17:0(2R-OH) Ceramide (CAS 1246298-46-3)
- D-Ser32-Tirzepatide (CAS CATO-CPTD788677)
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