Dapagliflozin Impurity 48 CAS CATO-C4X-113848
| CAS No. | CATO-C4X-113848 |
| Molecular Formula | C22H27IO5 |
| Molecular Weight | 498.35 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Dapagliflozin Impurity 48 (C22H27IO5) contains a flavonoid core, a hydroxyl group, an ether linkage, iodine substitution. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO supplies Dapagliflozin Impurity 48 (CAS CATO-C4X-113848), a pharmacopoeial impurity reference standard (molecular formula C22H27IO5, MW 498.35 g/mol) used for the identification and quantification of trace impurities in APIs.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C22H27IO5 |
| Molecular Weight | 498.35 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | I-containing |
Related Dapagliflozin Standards
- Dapagliflozin Impurity 131 (CAS CATO-C4X-1138131)
- Dapagliflozin Impurity 72 (CAS CATO-C4X-113872)
- Dapagliflozin Impurity 24 (CAS 2176485-21-3)
- Dapagliflozin Impurity 190 (CAS CATO-C4X-1138190)
- Dapagliflozin Impurity 81 (CAS CATO-C4X-113881)
- Dapagliflozin Impurity 138 (CAS CATO-C4X-1138138)
- Dapagliflozin Impurity 83 (CAS CATO-C4X-113883)
- Dapagliflozin Impurity 116 (CAS CATO-C4X-1138116)
Recommended Standards
- 3-((2,4-Dichlorobenzyl)thio)-4-ethyl-5-(1-phenyl-5-(trifluoromethyl)-1H-pyrazol-4-yl)-4H-1,2,4-triazole (CAS 778579-08-1)
- N-(4-bromo-2-methylphenyl)-2-((3-cyano-4-(trifluoromethyl)-6,7,8,9-tetrahydro-5H-cyclohepta[b]pyridin-2-yl)thio)acetamide (CAS 626227-38-1)
- 1,4-Bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2,5-dihexylbenzene (CAS 374934-77-7)
- 3-Bromo-5-Methyl-6-Nitro-1-Trityl-1H-Indazole (CAS 1695537-77-9)
- Azilsartan Methyl Ester Impurity (CAS 147403-52-9)
- Pemetrexed Impurity 50 (CAS CATO-C4X-172650)
- Propofol EP Impurity D (CAS 35946-91-9)
- 3,4-Dichloro-N-(4-chloro-5-cyanothiazol-2-yl)benzamide (CAS 866154-04-3)
- [(2S)-2-[[(1,1-Dimethylethoxy)carbonyl]amino]-3-phenylpropyl]-carbamicacid phenylmethylester (CAS 835916-04-6)
- ethyl 3-(6-chloro-2-methylpyrimidin-4-yl)propanoate (CAS 1909314-16-4)
- 5-Bromo-2-methoxy-4-methylpyrimidine (CAS 38696-23-0)
- Octahydrofuro[3,2-c]pyridine hydrochloride (CAS 1360363-68-3)
- 2-((1-(3-Fluorophenyl)ethyl)amino)propane-1,3-diol (CAS 1479640-68-0)
- Semaglutide impurity 214 (CAS CATO-C4X-2226214)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com