Lenvatinib Impurity 84 CAS CATO-C4X-114084
| CAS No. | CATO-C4X-114084 |
| Molecular Formula | C21H19ClN4O5 |
| Molecular Weight | 442.85 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO supplies Lenvatinib Impurity 84 (CAS CATO-C4X-114084), a pharmacopoeial impurity reference standard (molecular formula C21H19ClN4O5, MW 442.85 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C21H19ClN4O5, Lenvatinib Impurity 84 contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 442.85 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), Lenvatinib Impurity 84 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C21H19ClN4O5 |
| Molecular Weight | 442.85 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
Related Lenvatinib Standards
- Lenvatinib Impurity 5 (CAS 1788901-86-9)
- Lenvatinib Impurity 86 (CAS CATO-C4X-114086)
- Lenvatinib Impurity 138 (CAS CATO-C4X-1140138)
- Lenvatinib Impurity 139 (CAS CATO-C4X-1140139)
- Lenvatinib Impurity 28 (CAS 417717-20-5)
- Lenvatinib Impurity 179 (CAS CATO-C4X-1140179)
- Lenvatinib Impurity 66 (CAS CATO-C4X-114066)
- Lenvatinib Impurity 7 (CAS 2250242-56-7)
Recommended Standards
- N-(4-Chloro-3-(trifluoromethyl)phenyl)-2-((4-ethyl-5-(pyrazin-2-yl)-4H-1,2,4-triazol-3-yl)thio)acetamide (CAS 618427-30-8)
- Rebamipide Impurity 41 (CAS CATO-C4X-152341)
- 4-(4-Chlorobenzoyl)-3-hydroxy-5-(4-nitrophenyl)-1-((tetrahydrofuran-2-yl)methyl)-1H-pyrrol-2(5H)-one (CAS 488804-17-7)
- Rebamipide Impurity 45 (CAS CATO-C4X-152345)
- Bromazepam EP Impurity D (CAS 77616-97-8)
- Isavuconazole Impurity 113 (CAS CATO-C4X-1236113)
- Edoxaban Impurity 110 (CAS 45644-21-1)
- Perphenazine EP Impurity B (CAS 3533-97-9)
- 5-Methoxyisoquinoline-3-carbonitrile (CAS 1782905-41-2)
- 3-(aminomethyl)-1λ⁶-thiane-1,1-dione (CAS 933734-59-9)
- 5-[1-Thiophen-2-yl-meth-(E)-ylidene]-imidazolidine-2,4-dione (CAS 89939-28-6)
- (2R,3R,4S,5R,6S)-2-(acetoxymethyl)-6-chlorotetrahydro-2H-pyran-3,4,5-triyl triacetate (CAS 4451-36-9)
- Tert-butyl (S)-(1-cyano-2-methylpropyl)carbamate (CAS 216319-90-3)
- Biotinyl-S6 Phosphate Acceptor Peptide trifluoroacetate salt (CAS 1815618-12-2)
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