Sitafloxacin impurity 80 CAS CATO-C4X-115580
| CAS No. | CATO-C4X-115580 |
| Molecular Formula | C19H20ClF2N3O3 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Based on its molecular formula C19H20ClF2N3O3HCl, Sitafloxacin impurity 80 contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 448.29 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO supplies Sitafloxacin impurity 80 (CAS CATO-C4X-115580), a pharmacopoeial impurity reference standard (molecular formula C19H20ClF2N3O3HCl, MW 448.29 g/mol) used for the identification and quantification of trace impurities in APIs.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C19H20ClF2N3O3 HCl |
| Molecular Weight | 448.29 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
Related Sitafloxacin Standards
- Sitafloxacin Impurity 22 (CAS 101987-86-4)
- Sitafloxacin Impurity 25 (CAS 105919-35-5)
- Sitafloxacin impurity 90 (CAS 112062-51-8)
- Sitafloxacin Impurity 27 (CAS 119385-80-7)
- Sitafloxacin Impurity 17 (CAS 127199-00-2)
- Sitafloxacin Isomer Impurity 4(RSR) (CAS 127199-06-8)
- Sitafloxacin impurity 85 (CAS 127199-06-8（free base）)
- Sitafloxacin Impurity 23 (CAS 127199-15-9)
Recommended Standards
- Etoposide Impurity 29 (CAS CATO-C4X-202429)
- Ixazomib Impurity 28 (CAS CATO-C4X-126728)
- Dicyclomine impurity N1 (CAS 109158-77-2)
- Ethyl 4-formyl-1-methyl-1H-imidazole-5-carboxylate (CAS 2111324-86-6)
- 2-(4-Butylbenzamido)thiophene-3-carboxylic acid (CAS 1098375-06-4)
- 2-Bromo-N-(5-((2-((4-fluorophenyl)amino)-2-oxoethyl)thio)-1,3,4-thiadiazol-2-yl)benzamide (CAS 392297-58-4)
- 3,3-dichloroprop-2-en-1-amine hydrochloride (CAS 55233-81-3)
- 2,5-Dichloro-3-methylbenzaldehyde (CAS 1160573-34-1)
- 762-48-1 ACMC-209ols Ethyl 2-Amino-4-Methylthiazole-5-Carboxylate (CAS 762-48-1)
- Peptide T (CAS 106362-32-7)
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