Diosmin EP Impurity E-13C-d3 (Linarin-13C-d3) CAS CATO-C4X-115614

Description

The occurrence of Diosmin EP Impurity E-13C-d3 (Linarin-13C-d3) is closely related to deuterium isotope labeling, a carboxylic acid group, a hydroxyl group, an ether linkage, a polycyclic aromatic system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

CATO supplies Diosmin EP Impurity E-13C-d3 (Linarin-13C-d3) (CAS CATO-C4X-115614), a pharmacopoeial impurity reference standard (molecular formula C27[13C]H29D3O14, MW 596.56 g/mol) used for the identification and quantification of trace impurities in APIs.

Based on its molecular formula C27[13C]H29D3O14, Diosmin EP Impurity E-13C-d3 (Linarin-13C-d3) contains deuterium isotope labeling, a carboxylic acid group, a hydroxyl group, an ether linkage, a polycyclic aromatic system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 596.56 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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