Cholic Acid Impurity 27 CAS CATO-C4X-116027
| CAS No. | CATO-C4X-116027 |
| Molecular Formula | C28H36O2 |
| Molecular Weight | 404.58 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
As a process- or degradation-related impurity, Cholic Acid Impurity 27 (CAS CATO-C4X-116027, C28H36O2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Cholic Acid Impurity 27 (C28H36O2) contains a steroid core, a hydroxyl group, an ether linkage. Its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C28H36O2 |
| Molecular Weight | 404.58 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
Related Cholic Standards
- Cholic Acid Impurity 28 (CAS CATO-C4X-116028)
- Cholic Acid Impurity 52 (CAS 68170-81-0)
- Cholic Acid impurity 75 (CAS 2862-62-6)
- Cholic Acid Impurity 13 (CAS 2304-92-9)
- Cholic Aicd Impurity 17 (CAS 2304-91-8)
- Cholic Acid Impurity 18 (CAS 517-33-9)
- Cholic Acid Impurity 19 (CAS 2304-89-4)
- Cholic Acid Impurity 78 (CAS 79732-73-3)
Recommended Standards
- Obeticholic Acid Impurity 15 (CAS 10538-59-7)
- Methyl 7-β-Hydroxy-3-ketocholanoate (CAS 67371-28-2)
- Hexadecyl β-d-glucopyranoside, 98% (CAS 54549-27-8)
- Hexadecyl b-D-glucopyranoside (CAS 75319-63-0)
- Tenofovir disoproxil Impurity 90 (CAS 3084-40-0)
- Ivabradine Impurity 15 (CAS CATO-C4X-111915)
- Atracurium impurity 101 (CAS CATO-C4X-1850101)
- (3-(Tert-butyl)-5-(pyridin-4-yl)phenyl)boronic acid (CAS 2225169-82-2)
- 2-(Benzylthio)-1-((4-(tert-butyl)phenyl)sulfonyl)-1,4,5,6-tetrahydropyrimidine (CAS 866153-35-7)
- (4,5-Dihydro-1H-pyrazol-3-yl)triphenylphosphonium bromide (CAS 32251-61-9)
- (S)-3-Amino-4-hydroxybutan-2-one (CAS 1315052-42-6)
- 6-(Diethylsulfamoyl)-2-hydroxyquinoline-4-carboxylic acid (CAS 379730-31-1)
- (3,4-Dimethylphenyl)(3-hydroxyazetidin-1-yl)methanone (CAS 1342412-25-2)
- Semaglutide impurity 97 (CAS CATO-C4X-222697)
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