Dexamethasone Impurity 126 CAS CATO-C4X-1165126
| CAS No. | CATO-C4X-1165126 |
| Molecular Formula | C25H24N6O10S2 |
| Molecular Weight | 632.62 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Dexamethasone Impurity 126 (CAS CATO-C4X-1165126) is a certified pharmaceutical impurity reference standard with the molecular formula C25H24N6O10S2 and a molecular weight of 632.62 g/mol.
Structurally, Dexamethasone Impurity 126 (C25H24N6O10S2) contains a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 17.0, corresponding to approximately 17 ring(s) or double-bond equivalent(s). With a molecular weight of 632.62 g/mol, it falls into the high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Dexamethasone Impurity 126 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C25H24N6O10S2 |
| Molecular Weight | 632.62 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 17.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 6 |
| Sulfur Atoms | 2 |
Related Dexamethasone Standards
- Dexamethasone Impurity 101 (CAS CATO-C4X-1165101)
- Dexamethasone Impurity 99 (CAS CATO-C4X-116599)
- Dexamethasone 21-Palmitate (CAS 14899-36-6)
- Dexamethasone impurity 24 (CAS CATO-C4X-1165124)
- Dexamethasone heptadecanoate (CAS CATO-C4X-116575)
- Dexamethasone pentadecanoate (CAS CATO-C4X-116577)
- Dexamethasone Impurity 105 (CAS CATO-C4X-1165105)
- Dexamethasone Impurity 106 (CAS CATO-C4X-1165106)
Recommended Standards
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