Cefazedone impurity 18 CAS CATO-C4X-117118
| CAS No. | CATO-C4X-117118 |
| Molecular Formula | C17H15Cl2N3O7S |
| Molecular Weight | 476.29 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
As a process- or degradation-related impurity, Cefazedone impurity 18 (CAS CATO-C4X-117118, C17H15Cl2N3O7S) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Cefazedone impurity 18 (C17H15Cl2N3O7S) is characterized by a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C17H15Cl2N3O7S |
| Molecular Weight | 476.29 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Cefazedone Standards
- Cefazedone Impurity 2 (CAS 56187-36-1)
- Cefazedone Impurity 10 (CAS CATO-C4X-117110)
- Cefazedone Impurity 9 (CAS CATO-C4X-11719)
- Cefazedone Impurity 12 (CAS 788106-07-0)
- Cefazedone impurity 17 (CAS CATO-C4X-117117)
- Cefazedone Impurity 12 (CAS CATO-C4X-117112)
- Cefazedone impurity 16 (CAS CATO-C4X-117116)
- Cefazedone Impurity 3 (CAS 70149-63-2)
Recommended Standards
- 6-Chloro-1-(2-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}ethyl)-3-[(2-methoxyethyl)amino]-1,2-dihydroquinoxalin-2-one (CAS 303986-16-5)
- 4-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-N-[(1E)-{[(4-chlorophenyl)methoxy]amino}methylidene]piperazine-1-carboxamide (CAS 338979-05-8)
- 1-[1-(3,5-Dichlorophenyl)-5-(4-methanesulfonylphenyl)-2-methyl-1H-pyrrol-3-yl]-2,2,2-trifluoroethan-1-one (CAS 478043-48-0)
- Dabrafenib Impurity 10 (CAS CATO-C4X-303310)
- Olanzapine Embonate Monohydrate EP Impurity F (CAS CATO-C4X-117863)
- Crizotinib impurity 34 (CAS CATO-C4X-102534)
- Josamycin Impurity 11 (CAS 31674-19-8)
- 1H-pyrazolo[1,5-a]imidazole-7-carboxylic acid hydrochloride (CAS 222055-81-4)
- Boc-2-(trifluoromethyl)-L-phenylalanine (CAS 167993-21-7)
- 2-(4-(Trifluoromethyl)phenyl)piperazine dihydrochloride (CAS 1171352-39-8)
- 4-Isothiocyanato-1-methyl-1H-pyrazole (CAS 1001500-53-3)
- 1,2-Dimethyl-3,4-dinitrobenzene (CAS 603-06-5)
- Allyl 2-acetamido-2-deoxy-β-D-glucopyranoside (CAS 54400-77-0)
- Tirzepatide Impurity 9 (CAS CATO-C4X-32409)
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