Cefazedone Impurity 8 Formate CAS CATO-C4X-11718
| CAS No. | CATO-C4X-11718 |
| Molecular Formula | C18H15Cl2N5O6S3 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Cefazedone Impurity 8 Formate (CAS CATO-C4X-11718, C18H15Cl2N5O6S3CH2O2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Cefazedone Impurity 8 Formate (C18H15Cl2N5O6S3CH2O2) contains a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C18H15Cl2N5O6S3 CH2O2 |
| Molecular Weight | 610.45 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 5 |
| Sulfur Atoms | 3 |
Related Cefazedone Standards
- Cefazedone Impurity 1 Sodium Salt (CAS 14441-14-6)
- Cefazedone Impurity 16 (CAS 17228-71-6)
- Cefazedone impurity 15 (CAS 3004928-24-6)
- Cefazedone Impurity 2 (CAS 56187-36-1)
- Cefazedone Impurity 13 (CAS 56187-37-2)
- Cefazedone (CAS 56187-47-4)
- Cefazedone Impurity 14 (CAS 57457-59-7)
- Cefazedone Sodium Salt (CAS 63521-15-3)
Recommended Standards
- Lubiprostone Impurity 40 (CAS CATO-C4X-113640)
- Fenofibrate EP Impurity F (CAS 154356-96-4)
- Diclofenac Sodium Impurity 32 (CAS 4746-61-6)
- 4-(4-Methoxyphenyl)-5-methylpyrimidin-2-amine (CAS 61541-78-4)
- 2-(tert-Butyl)-4-chlorothiazole (CAS 1893671-31-2)
- 4,4'-Bipiperidine (CAS 15336-72-8)
- 4,4,4,4',4',4'-Hexafluorovaline hydrochloride (CAS 1214705-90-4)
- 3-Cyclopropoxy-5-isopropoxybenzamide (CAS 1243350-23-3)
- trans-3-(Boc-amino)-5-methylpiperidine (CAS 1405128-25-7)
- (Tyr?)-C-Peptide (dog) (CAS 101135-67-5)
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