Cefazedone Impurity 14 CAS 57457-59-7
| CAS No. | 57457-59-7 |
| Molecular Formula | C10H14N2O6S |
| Molecular Weight | 290.29 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Cefazedone Impurity 14 (CAS 57457-59-7) is a certified pharmaceutical impurity reference standard with the molecular formula C10H14N2O6S and a molecular weight of 290.29 g/mol.
The molecular framework of Cefazedone Impurity 14 (C10H14N2O6S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Cefazedone Impurity 14 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H14N2O6S |
| Molecular Weight | 290.29 g/mol |
| Purity | ≥90% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1973 |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Cefazedone Standards
- Cefazedone Impurity 11 (CAS CATO-C4X-117111)
- Cefazedone impurity 15 (CAS 3004928-24-6)
- Cefazedone Impurity 23 (CAS 64485-88-7)
- Cefazedone Impurity 13 (CAS 56187-37-2)
- Cefazedone lactone (CAS 70150-41-3)
- Cefazedone Impurity 16 (CAS 17228-71-6)
- Cefazedone impurity 16 (CAS CATO-C4X-117116)
- Cefazedone Impurity 3 (CAS 70149-63-2)
Recommended Standards
- Rosuvastatin Impurity 78 (CAS 488798-37-4)
- Flurbiprofen Impurity 111 (CAS CATO-C4X-1444111)
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- Cefotaxime EP Impurity C (CAS 66403-32-5)
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- 2,2-Dichloro-N-(4-(4-fluorophenyl)-6-methoxypyrimidin-2-yl)acetamide (CAS 648410-29-1)
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- 4-Bromo-3-difluoromethoxy-5-nitrotoluene (CAS 1805104-01-1)
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