Salbutamol Impurity 128 CAS CATO-C4X-1176128
| CAS No. | CATO-C4X-1176128 |
| Molecular Formula | C21H29NO3 |
| Molecular Weight | 343.46 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Salbutamol Impurity 128 is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Salbutamol Impurity 128 (CAS CATO-C4X-1176128) is a certified pharmaceutical impurity reference standard with the molecular formula C21H29NO3 and a molecular weight of 343.46 g/mol.
The molecular framework of Salbutamol Impurity 128 (C21H29NO3) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Salbutamol Impurity 128 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C21H29NO3 |
| Molecular Weight | 343.46 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 1 |
Related Salbutamol Standards
- Salbutamol Impurity 120 (CAS CATO-C4X-1176120)
- Salbutamol Impurity 101 (CAS CATO-C4X-1176101)
- Salbutamol Impurity 135 (CAS CATO-C4X-1176135)
- Salbutamol Impurity 136 (CAS CATO-C4X-1176136)
- Salbutamol Impurity 137 (CAS CATO-C4X-1176137)
- Salbutamol Impurity 24 (CAS CATO-C4X-117624)
- Salbutamol Impurity 88 (CAS 156339-89-8)
- Salbutamol Impurity 57 (CAS CATO-C4X-1176157)
Recommended Standards
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- Lanthanum(III) chloride hexahydrate (CAS 17272-45-6)
- Neuropeptide K, porcine (CAS 106441-70-7)
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